Low Flow versus No Flow: Ischaemia Reperfusion Injury Following Different Experimental Models in the Equine Small Intestine.

apoptosis colic horse inflammation intestine ischaemia reperfusion

Journal

Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614

Informations de publication

Date de publication:
22 Aug 2022
Historique:
received: 16 07 2022
revised: 17 08 2022
accepted: 19 08 2022
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 27 8 2022
Statut: epublish

Résumé

In experimental studies investigating strangulating intestinal lesions in horses, different ischaemia models have been used with diverging results. Therefore, the aim was to comparatively describe ischaemia reperfusion injury (IRI) in a low flow (LF) and no flow (NF) model. Under general anaesthesia, 120 min of jejunal ischaemia followed by 120 min of reperfusion was induced in 14 warmbloods. During ischaemia, blood flow was reduced by 80% (LF,

Identifiants

pubmed: 36009747
pii: ani12162158
doi: 10.3390/ani12162158
pmc: PMC9405230
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Anna Marei Grages (AM)

Clinic for Horses, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Nicole Verhaar (N)

Clinic for Horses, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Christiane Pfarrer (C)

Institute for Anatomy, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Gerhard Breves (G)

Institute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Marion Burmester (M)

Institute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Stephan Neudeck (S)

Small Animal Clinic, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Sabine Kästner (S)

Clinic for Horses, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Small Animal Clinic, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.

Classifications MeSH