Clinical Characteristics of Venous Thrombosis Associated with Peripherally Inserted Central Venous Catheter in Premature Infants.

anticoagulation therapy autoimmune disease preterm infants venous thrombosis

Journal

Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936

Informations de publication

Date de publication:
28 Jul 2022
Historique:
received: 22 06 2022
revised: 25 07 2022
accepted: 27 07 2022
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 27 8 2022
Statut: epublish

Résumé

This study aimed to analyze clinical characteristics and risk factors for peripherally inserted central catheter (PICC) placement in premature infants. This study included seven premature infants who were hospitalized in the neonatal intensive care unit (NICU) of Peking University Third Hospital from 1 January 2014-30 June 2021, and suffered PICC-related venous thrombosis. The control group included premature infants ( The incidence of PICC-related thrombus was 0.23% (7/3043. Univariate analysis revealed that, compared to the non-thrombotic group, mothers in the thrombosis group had autoimmune diseases (χ PICC-related thrombosis occurred within 1 week after catheter placement, and thrombosis more likely happened in infants whose mothers had autoimmune disease. When this high-risk factor exists and the patient has been intubated for 1 week and has sudden swelling in the intubated limb, venous ultrasound should be performed immediately to diagnose, and treatment should be provided in a timely manner to reduce adverse events.

Sections du résumé

BACKGROUND BACKGROUND
This study aimed to analyze clinical characteristics and risk factors for peripherally inserted central catheter (PICC) placement in premature infants.
MATERIALS METHODS
This study included seven premature infants who were hospitalized in the neonatal intensive care unit (NICU) of Peking University Third Hospital from 1 January 2014-30 June 2021, and suffered PICC-related venous thrombosis. The control group included premature infants (
RESULTS RESULTS
The incidence of PICC-related thrombus was 0.23% (7/3043. Univariate analysis revealed that, compared to the non-thrombotic group, mothers in the thrombosis group had autoimmune diseases (χ
CONCLUSIONS CONCLUSIONS
PICC-related thrombosis occurred within 1 week after catheter placement, and thrombosis more likely happened in infants whose mothers had autoimmune disease. When this high-risk factor exists and the patient has been intubated for 1 week and has sudden swelling in the intubated limb, venous ultrasound should be performed immediately to diagnose, and treatment should be provided in a timely manner to reduce adverse events.

Identifiants

pubmed: 36010017
pii: children9081126
doi: 10.3390/children9081126
pmc: PMC9406451
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Kathmandu Univ Med J (KUMJ). 2010 Jan-Mar;8(29):87-90
pubmed: 21209514
J Med Life. 2021 May-Jun;14(3):298-309
pubmed: 34377194
Intensive Care Med. 2017 Mar;43(3):452-454
pubmed: 28194512
Neurocrit Care. 2008;8(3):471-5
pubmed: 18357420
Eur J Heart Fail. 2020 May;22(5):906-910
pubmed: 32232914
Eur J Rheumatol. 2019 Dec 03;:1-10
pubmed: 31804173
JAMA Intern Med. 2022 Jan 1;182(1):50-58
pubmed: 34842905
Arch Argent Pediatr. 2016 Apr;114(2):159-66
pubmed: 27079395
Lupus. 2007;16(8):634-41
pubmed: 17711900
Thromb Res. 2019 Sep;181 Suppl 1:S33-S36
pubmed: 31477225
J Vasc Access. 2021 Jul 28;:11297298211034308
pubmed: 34320846
PLoS One. 2021 Jul 23;16(7):e0255090
pubmed: 34297756
Clin Nutr. 2000 Aug;19(4):237-43
pubmed: 10952794
Blood Cells Mol Dis. 2017 Sep;67:34-40
pubmed: 28283251
Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):399-404
pubmed: 30504338
Chest. 2012 Feb;141(2 Suppl):e737S-e801S
pubmed: 22315277
BMJ Open. 2019 Aug 22;9(8):e026031
pubmed: 31444177

Auteurs

Weiwei Zhu (W)

Pediatric Department, Peking University Third Hospital, Beijing 100191, China.

Hua Zhang (H)

Clinical Epidemiology Research Center, Peking University Third Hospital, Beijing 100191, China.

Yan Xing (Y)

Pediatric Department, Peking University Third Hospital, Beijing 100191, China.

Classifications MeSH