Management of Recurrent Meningiomas: State of the Art and Perspectives.
meningioma
overall survival
progression-free survival
recurrence
retreatment
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
18 Aug 2022
18 Aug 2022
Historique:
received:
24
07
2022
revised:
12
08
2022
accepted:
16
08
2022
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
While meningiomas often recur over time, the natural history of repeated recurrences and their management are not well described. Should recurrence occur, repeat surgery and/or use of adjuvant therapeutic options may be necessary. Here, we summarize current practice when it comes to meningioma recurrence after initial surgical management. A total of N = 89 articles were screened. N = 41 articles met the inclusion criteria and N = 16 articles failed to assess management of meningioma recurrence. Finally, N = 24 articles were included in our review. The articles were distributed as follows: studies on chemotherapy (N = 14), radiotherapy, protontherapy, and stereotaxic radiosurgery (N = 6), boron-neutron capture therapy (N = 2) and surgery (N = 3). No study seems to provide serious alternatives to surgery in terms of progression-free and overall survival. Recurrence can occur long after the initial surgery and also affects WHO grade 1 meningiomas, even after initial gross total resection at first surgery, emphasizing the need for a long-term and comprehensive follow-up. Surgery still seems to be the state-of-the-art management when it comes to meningioma recurrence, since none of the non-surgical alternatives show promising results in terms of progression-free and overall survival.
Sections du résumé
BACKGROUND
BACKGROUND
While meningiomas often recur over time, the natural history of repeated recurrences and their management are not well described. Should recurrence occur, repeat surgery and/or use of adjuvant therapeutic options may be necessary. Here, we summarize current practice when it comes to meningioma recurrence after initial surgical management.
METHODS
METHODS
A total of N = 89 articles were screened. N = 41 articles met the inclusion criteria and N = 16 articles failed to assess management of meningioma recurrence. Finally, N = 24 articles were included in our review.
RESULTS
RESULTS
The articles were distributed as follows: studies on chemotherapy (N = 14), radiotherapy, protontherapy, and stereotaxic radiosurgery (N = 6), boron-neutron capture therapy (N = 2) and surgery (N = 3). No study seems to provide serious alternatives to surgery in terms of progression-free and overall survival. Recurrence can occur long after the initial surgery and also affects WHO grade 1 meningiomas, even after initial gross total resection at first surgery, emphasizing the need for a long-term and comprehensive follow-up.
CONCLUSIONS
CONCLUSIONS
Surgery still seems to be the state-of-the-art management when it comes to meningioma recurrence, since none of the non-surgical alternatives show promising results in terms of progression-free and overall survival.
Identifiants
pubmed: 36010988
pii: cancers14163995
doi: 10.3390/cancers14163995
pmc: PMC9406695
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
J Natl Cancer Inst. 2015 Dec 13;108(5):
pubmed: 26668184
Cancer Chemother Pharmacol. 2016 Jan;77(1):115-20
pubmed: 26659583
World Neurosurg. 2015 Sep;84(3):839-45
pubmed: 25916182
Neuro Oncol. 2016 Mar;18(3):401-7
pubmed: 26354929
J Neurosurg. 1983 Jan;58(1):51-6
pubmed: 6847909
J Neurooncol. 2006 Jul;78(3):271-6
pubmed: 16628476
J Neurol Surg B Skull Base. 2018 Oct;79(Suppl 4):S322-S327
pubmed: 30210985
J Neurosurg. 1985 Jan;62(1):18-24
pubmed: 3964853
Acta Neurochir (Wien). 2022 Jan;164(1):229-238
pubmed: 34714434
Neuro Oncol. 2021 Nov 2;23(11):1821-1834
pubmed: 34181733
J Clin Med. 2019 Dec 31;9(1):
pubmed: 31906133
Radiology. 2014 Mar;270(3):834-41
pubmed: 24475844
Neurosurgery. 1996 Jul;39(1):2-7; discussion 8-9
pubmed: 8805134
Int J Radiat Oncol Biol Phys. 2012 Jul 1;83(3):865-71
pubmed: 22138457
BMJ. 2016 Mar 08;352:i1152
pubmed: 26957104
Int J Radiat Oncol Biol Phys. 2017 Dec 1;99(5):1190-1198
pubmed: 28939227
J Neurol Neurosurg Psychiatry. 1957 Feb;20(1):22-39
pubmed: 13406590
Neuro Oncol. 2022 Jan 5;24(1):90-98
pubmed: 33984146
Trials. 2015 Nov 14;16:519
pubmed: 26576533
Eur J Nucl Med Mol Imaging. 2012 Sep;39(9):1409-15
pubmed: 22669255
Acta Neurochir (Wien). 2017 Dec;159(12):2391-2400
pubmed: 29064038
BMJ. 2021 Mar 29;372:n71
pubmed: 33782057
Acta Neurochir (Wien). 2020 Mar;162(3):631-640
pubmed: 31834502
J Neurosurg. 2007 Jan;106(1):30-5
pubmed: 17236485
Acta Neurochir (Wien). 2021 Dec;163(12):3387-3400
pubmed: 34398339
J Neurosurg. 2012 Dec;117(6):999-1006
pubmed: 23061394
Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):222-7
pubmed: 16488553
World Neurosurg. 2019 Feb;122:e1275-e1284
pubmed: 30447439
J Neurosurg. 2016 Sep;125(3):551-60
pubmed: 26824369
Neurosurgery. 2019 Nov 1;85(5):E910-E916
pubmed: 31329941
J Neurooncol. 2014 Mar;117(1):93-101
pubmed: 24449400
BMC Cancer. 2022 Apr 7;22(1):367
pubmed: 35392834
J Neurooncol. 2016 Sep;129(2):281-8
pubmed: 27311730
Neurosurg Rev. 2019 Dec;42(4):961-972
pubmed: 29978438
Neurosurgery. 2005 Jul;57(1 Suppl):107-13; discussion 107-13
pubmed: 15987576
Surg Neurol. 1986 Nov;26(5):461-9
pubmed: 3764651
Cancers (Basel). 2021 Sep 24;13(19):
pubmed: 34638276
Acta Neurochir (Wien). 1999;141(9):933-40
pubmed: 10526074
Neurosurg Rev. 2020 Dec;43(6):1547-1553
pubmed: 31664581
J Neurosurg. 2018 May 4;130(3):876-883
pubmed: 29726777
Neuro Oncol. 2019 Jul 11;21(7):901-910
pubmed: 31158293
J Neurosurg. 2012 Dec;117(6):997-8; discussion 998
pubmed: 23061390
J Neurosurg. 1986 Aug;65(2):168-71
pubmed: 3723173
Neurosurg Rev. 2019 Mar;42(1):163-173
pubmed: 29627874
Int J Radiat Oncol Biol Phys. 2012 Aug 1;83(5):e633-7
pubmed: 22768992
AJNR Am J Neuroradiol. 2021 Aug;42(8):1421-1428
pubmed: 34117017
Cancer. 2015 Dec 15;121(24):4376-81
pubmed: 26308667
J Neurosurg. 2004 Jun;100(6):1002-13
pubmed: 15200115
Eur J Nucl Med Mol Imaging. 2009 Sep;36(9):1407-16
pubmed: 19319527
Lancet Oncol. 2017 May;18(5):682-694
pubmed: 28314689
Int J Radiat Oncol Biol Phys. 2011 Dec 1;81(5):1428-35
pubmed: 20934263
Acta Neurochir (Wien). 2022 May;164(5):1381-1383
pubmed: 35067786
World Neurosurg. 2016 Feb;86:210-9
pubmed: 26428319
Neurosurg Rev. 2020 Apr;43(2):749-758
pubmed: 31183587
J Korean Neurosurg Soc. 2012 Dec;52(6):517-22
pubmed: 23346322
Brain Tumor Res Treat. 2021 Oct;9(2):46-57
pubmed: 34725984
Radiat Oncol. 2018 Mar 27;13(1):54
pubmed: 29587795
Acta Neurochir (Wien). 2021 Jun;163(6):1639-1663
pubmed: 33740134
Clin Neurol Neurosurg. 2016 Feb;141:117-21
pubmed: 26780494
Radiother Oncol. 2004 Jun;71(3):251-8
pubmed: 15172139
Neuro Oncol. 2015 Jan;17(1):116-21
pubmed: 25100872
J Neurosurg. 2020 Oct 9;:1-8
pubmed: 33035995
Adv Radiat Oncol. 2021 Dec 24;7(3):100878
pubmed: 35647401
Cancers (Basel). 2021 Mar 22;13(6):
pubmed: 33810089
J Neurosurg. 1986 Jan;64(1):58-63
pubmed: 3941351
Sci Rep. 2019 Apr 11;9(1):5944
pubmed: 30976047
J Neurosurg. 2002 Aug;97(2):341-6
pubmed: 12186462
J Neurol Surg B Skull Base. 2019 Feb;80(1):59-66
pubmed: 30733902
Acta Neurochir (Wien). 2019 May;161(5):1003-1011
pubmed: 30859321
Cancer Chemother Pharmacol. 2014 May;73(5):919-23
pubmed: 24619496
PLoS One. 2019 Jun 20;14(6):e0217340
pubmed: 31220093
Cancer. 2018 Feb 15;124(4):734-742
pubmed: 29131312
J Clin Neurosci. 2011 Jul;18(7):895-8
pubmed: 21565513
J Clin Neurosci. 2012 Sep;19(9):1261-4
pubmed: 22784877
J Neurooncol. 2012 Jan;106(2):409-15
pubmed: 21938530
Clin Cancer Res. 2020 Feb 1;26(3):552-557
pubmed: 31969329
Neuro Oncol. 2021 May 5;23(5):783-794
pubmed: 33068421
J Nucl Med. 2015 Nov;56(11):1748-51
pubmed: 26294303
World Neurosurg. 2011 Dec;76(6):564-71
pubmed: 22251505
Neurosurgery. 2020 Dec 15;88(1):140-146
pubmed: 32827256
Sci Rep. 2020 Jan 15;10(1):303
pubmed: 31941981
J Neurooncol. 2017 Jul;133(3):641-651
pubmed: 28527009
Acta Neurochir (Wien). 2010 Jul;152(7):1099-116
pubmed: 20419460
Neurology. 2015 Jan 20;84(3):280-6
pubmed: 25527270
Clin Neurol Neurosurg. 2021 Aug;207:106808
pubmed: 34293659
Int J Radiat Oncol Biol Phys. 2001 Jan 1;49(1):99-105
pubmed: 11163502
Neurochirurgie. 2020 Apr;66(2):73-79
pubmed: 32145249