Good Long-Term Prognosis of Lupus Nephritis in the High-Income Afro-Caribbean Population of Martinique with Free Access to Healthcare.
Afro-Caribbean
end-stage renal disease
long-term prognosis
lupus nephritis
mortality
systemic lupus
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
19 Aug 2022
19 Aug 2022
Historique:
received:
28
03
2022
revised:
12
05
2022
accepted:
18
05
2022
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
Lupus nephritis (LN) has been described as having worse survival and renal outcomes in African-descent patients than Caucasians. We aimed to provide long-term population-based data in an Afro-descendant cohort of LN with high income and easy and free access to specialized healthcare. We performed a retrospective population-based analysis using data from 2002-2015 of 1140 renal biopsies at the University Hospital of Martinique (French West Indies). All systemic lupus erythematosus patients with a diagnosis of LN followed for at least 12 months in Martinique or who died during this period were included. A total of 89 patients were included, of whom 68 (76.4%) had proliferative (class III or IV), 17 (19.1%) had membranous (class V), and 4 (4.5%) had class I or II lupus nephritis according to the ISN/RPS classification. At a mean follow-up of 118.3 months, 51.7% of patients were still in remission. The rates of end-stage renal disease were 13.5%, 19.1%, and 21.3% at 10, 15, and 20 years of follow-up, respectively, and mortality rates were 4.5%, 5.6%, and 7.9% at 10, 15, and 20 years of follow-up, respectively. The good survival of our Afro-descendant LN patients, similar to that observed in Caucasians, shades the burden of ethnicity but rather emphasizes and reinforces the importance of optimizing all modifiable factors associated with poor outcome, especially socioeconomics.
Identifiants
pubmed: 36013099
pii: jcm11164860
doi: 10.3390/jcm11164860
pmc: PMC9410092
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Lupus. 2006;15(10):662-70
pubmed: 17120593
Medicine (Baltimore). 2006 May;85(3):147-156
pubmed: 16721257
Arthritis Rheum. 2002 Aug;46(8):2121-31
pubmed: 12209517
Arthritis Care Res (Hoboken). 2015 Oct;67(10):1453-62
pubmed: 25624071
Kidney Int. 2004 Feb;65(2):521-30
pubmed: 14717922
Arthritis Rheum. 2007 Aug 15;57(6):993-9
pubmed: 17665464
J Nephrol. 2008 Jul-Aug;21(4):570-5
pubmed: 18651548
Arthritis Care Res. 2000 Dec;13(6):406-8
pubmed: 14635317
Ann Rheum Dis. 1992 Nov;51(11):1197-201
pubmed: 1466595
Nephrol Dial Transplant. 2003 Oct;18(10):2039-46
pubmed: 13679478
J Am Soc Nephrol. 2007 Jan;18(1):244-54
pubmed: 17167111
Am J Med. 1991 Oct;91(4):345-53
pubmed: 1951378
Ann Rheum Dis. 2016 Mar;75(3):526-31
pubmed: 25757867
Ann Rheum Dis. 2003 May;62(5):435-9
pubmed: 12695156
J Rheumatol. 2010 Jun;37(6):1158-63
pubmed: 20395647
Lupus. 2015 Mar;24(3):331-8
pubmed: 25609684
Rheumatology (Oxford). 2016 Feb;55(2):252-62
pubmed: 26342222
Medicine (Baltimore). 2003 Sep;82(5):299-308
pubmed: 14530779
J Rheumatol. 2006 Aug;33(8):1563-9
pubmed: 16881113
Arthritis Care Res (Hoboken). 2012 Aug;64(8):1151-8
pubmed: 22392730
Semin Arthritis Rheum. 2018 Oct;48(2):205-213
pubmed: 29458974
Lupus. 2006;15(1):26-31
pubmed: 16482742
Kidney Int. 1992 Sep;42(3):743-8
pubmed: 1405352
Arthritis Care Res (Hoboken). 2014 Apr;66(4):617-24
pubmed: 24124011
Lupus. 2011 Oct;20(11):1135-41
pubmed: 21719527
Arthritis Rheumatol. 2014 Feb;66(2):390-6
pubmed: 24504811
Medicine (Baltimore). 1999 May;78(3):148-66
pubmed: 10352647
Ann Rheum Dis. 2007 Sep;66(9):1168-72
pubmed: 17389655
J Rheumatol. 1994 Nov;21(11):2046-51
pubmed: 7869308
Arthritis Rheum. 1997 Jan;40(1):47-56
pubmed: 9008599
Kidney Int. 1997 Apr;51(4):1188-95
pubmed: 9083285
J Clin Rheumatol. 2008 Aug;14(4):195-201
pubmed: 18636020
Arthritis Rheum. 2011 Jun;63(6):1681-8
pubmed: 21445962
Rev Med Interne. 2002 Jan;23(1):21-9
pubmed: 11859691
Rheumatology (Oxford). 2010 Jan;49(1):128-40
pubmed: 19933596
J Rheumatol. 2001 Jun;28(6):1245-51
pubmed: 11414264
Arthritis Rheumatol. 2015 Mar;67(3):752-60
pubmed: 25590668
Ann Rheum Dis. 2000 Feb;59(2):116-9
pubmed: 10666166
Kidney Int. 2001 Jun;59(6):2156-63
pubmed: 11380817
Arthritis Rheumatol. 2017 Aug;69(8):1612-1622
pubmed: 28480630
Postgrad Med J. 1997 Apr;73(858):230-3
pubmed: 9156126
N Engl J Med. 2011 Nov 17;365(20):1886-95
pubmed: 22087680
Rheumatol Int. 2010 Aug;30(10):1311-5
pubmed: 19784840
Kidney Int. 2016 Sep;90(3):487-92
pubmed: 27344205
Lupus. 2002;11(3):152-60
pubmed: 12004788
Arthritis Care Res (Hoboken). 2010 Jun;62(6):873-80
pubmed: 20191478
Arthritis Rheumatol. 2016 Feb;68(2):441-8
pubmed: 26359794
Curr Opin Rheumatol. 2019 Nov;31(6):689-696
pubmed: 31436582
Am J Med Sci. 2007 Dec;334(6):426-30
pubmed: 18091363
J Rheumatol. 2005 May;32(5):913-9
pubmed: 15868630
Arthritis Rheum. 1987 Dec;30(12):1326-32
pubmed: 3435564
Ann Rheum Dis. 2010 Jan;69(1):61-4
pubmed: 19155235
Am J Kidney Dis. 2013 May;61(5):710-5
pubmed: 23375819
Nephrol Dial Transplant. 1995;10(9):1620-8
pubmed: 8559480
Rheumatology (Oxford). 2015 May;54(5):836-43
pubmed: 25323056
Arthritis Rheum. 1982 Jun;25(6):601-11
pubmed: 7092960
Lupus. 2006;15(10):689-94
pubmed: 17120598
Arthritis Rheumatol. 2014 Nov;66(11):3096-104
pubmed: 25403681
Arthritis Rheum. 1995 Feb;38(2):274-83
pubmed: 7848319
Clin J Am Soc Nephrol. 2014 Feb;9(2):279-84
pubmed: 24262502
Lupus. 1993 Jun;2(3):173-6
pubmed: 8369808
J Gen Intern Med. 2012 Oct;27(10):1326-33
pubmed: 22588825
Lupus. 1995 Apr;4(2):109-15
pubmed: 7795613
Lupus. 2002;11(3):161-7
pubmed: 11999880
Ann Rheum Dis. 2013 Aug;72(8):1280-6
pubmed: 23740227