Non-Immunologic Causes of Late Death-Censored Kidney Graft Failure: A Personalized Approach.
adherence to prescriptions
arterial hypertension
drug toxicities
dyslipidemia
hyperu
hyperuricemia
new onset diabetes mellitus
quality of the donated kidney
Journal
Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269
Informations de publication
Date de publication:
01 Aug 2022
01 Aug 2022
Historique:
received:
01
04
2022
revised:
28
07
2022
accepted:
28
07
2022
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
Despite continuous advances in surgical and immunosuppressive protocols, the long-term survival of transplanted kidneys is still far from being satisfactory. Antibody-mediated rejection, recurrent autoimmune diseases, and death with functioning graft are the most frequent causes of late-kidney allograft failure. However, in addition to these complications, a number of other non-immunologic events may impair the function of transplanted kidneys and directly or indirectly lead to their failure. In this narrative review, we will list and discuss the most important nonimmune causes of late death-censored kidney graft failure, including quality of the donated kidney, adherence to prescriptions, drug toxicities, arterial hypertension, dyslipidemia, new onset diabetes mellitus, hyperuricemia, and lifestyle of the renal transplant recipient. For each of these risk factors, we will report the etiopathogenesis and the potential consequences on graft function, keeping in mind that in many cases, two or more risk factors may negatively interact together.
Identifiants
pubmed: 36013220
pii: jpm12081271
doi: 10.3390/jpm12081271
pmc: PMC9410103
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Transplantation. 2000 Apr 27;69(8):1704-10
pubmed: 10836384
Cardiol Clin. 2021 Aug;39(3):353-363
pubmed: 34247749
Kidney Int. 2015 Feb;87(2):272-5
pubmed: 25635719
Am J Transplant. 2019 Dec;19(12):3240-3249
pubmed: 31152486
Front Med (Lausanne). 2021 Aug 10;8:697055
pubmed: 34447762
Transplantation. 2014 Apr 15;97(7):717-21
pubmed: 24342977
Kidney Int. 2000 Jul;58(1):293-301
pubmed: 10886574
Am J Physiol Renal Physiol. 2010 Aug;299(2):F336-46
pubmed: 20484295
JPEN J Parenter Enteral Nutr. 2001 May-Jun;25(3):120-31
pubmed: 11334061
Am J Transplant. 2018 Jan;18 Suppl 3:3-17
pubmed: 29292861
Am J Kidney Dis. 2010 Feb;55(2):335-43
pubmed: 19926370
Ann Pharmacother. 2021 Apr;55(4):496-508
pubmed: 32795145
Atherosclerosis. 2015 Feb;238(2):264-70
pubmed: 25544176
Nephrol Dial Transplant. 2007 Oct;22(10):3034-9
pubmed: 17517794
Curr Opin Organ Transplant. 2010 Jun;15(3):288-92
pubmed: 20445451
Am J Transplant. 2021 Apr;21(4):1391-1401
pubmed: 32594646
Kidney Int. 2021 Sep;100(3):536-545
pubmed: 33932457
Transpl Int. 2005 Oct;18(10):1121-33
pubmed: 16162098
Transplantation. 2018 Feb;102(2S Suppl 1):S44-S46
pubmed: 28230638
Am J Transplant. 2011 May;11(5):1064-70
pubmed: 21449948
Kidney Int. 2014 Feb;85(2):258-64
pubmed: 23965521
Transplant Proc. 2006 Sep;38(7):2314-6
pubmed: 16980076
Am J Cardiol. 2014 Aug 15;114(4):562-70
pubmed: 25001155
Curr Opin Nephrol Hypertens. 2003 Nov;12(6):599-605
pubmed: 14564196
Kidney Int. 2000 May;57(5):2144-50
pubmed: 10792636
Acta Diabetol. 2018 Aug;55(8):763-779
pubmed: 29619563
Am J Kidney Dis. 2012 Jun;59(6):841-8
pubmed: 22305759
N Engl J Med. 2008 Oct 23;359(17):1811-21
pubmed: 18946066
Kidney Int. 2009 Sep;76(5):528-33
pubmed: 19536081
Am J Transplant. 2012 Feb;12(2):388-99
pubmed: 22081892
JCI Insight. 2016 Jan 21;1(1):e85323
pubmed: 27699214
Transplant Rev (Orlando). 2020 Jan;34(1):100511
pubmed: 31627978
Clin Transplant. 2001 Feb;15(1):48-52
pubmed: 11168315
Med Sci (Basel). 2020 Nov 17;8(4):
pubmed: 33213078
J Nephrol. 2016 Oct;29(5):603-10
pubmed: 26956132
Nephrol Dial Transplant. 2016 Jun;31(6):890-6
pubmed: 25829326
Nat Med. 2015 Jan;21(1):37-46
pubmed: 25419705
J Clin Med. 2021 Oct 21;10(21):
pubmed: 34768354
Nephrol Dial Transplant. 2006 Jul;21 Suppl 3:iii14-7
pubmed: 16815851
BMC Infect Dis. 2016 Jun 10;16:264
pubmed: 27287058
Expert Opin Drug Saf. 2018 Apr;17(4):387-405
pubmed: 29468916
Curr Opin Nephrol Hypertens. 2004 Nov;13(6):607-11
pubmed: 15483450
Am J Kidney Dis. 2015 Dec;66(6):984-92
pubmed: 26209544
Transplantation. 2010 May 15;89(9):1057-70
pubmed: 20090569
Transplantation. 2005 Nov 27;80(10):1402-5
pubmed: 16340782
Am J Kidney Dis. 2016 Jun;67(6):881-92
pubmed: 26905361
JAMA. 2019 Oct 15;322(15):1486-1499
pubmed: 31613346
N Am J Med Sci. 2016 Jul;8(7):291-6
pubmed: 27583237
Eur J Heart Fail. 2014 Jan;16(1):15-24
pubmed: 23933579
J Immunol. 2015 Dec 15;195(12):5525-31
pubmed: 26637661
Am J Kidney Dis. 2004 Oct;44(4):642-50
pubmed: 15384015
Transplantation. 1997 Feb 15;63(3):331-8
pubmed: 9039919
Clin Pharmacol Ther. 2017 Jan;101(1):114-120
pubmed: 27804122
J Clin Hypertens (Greenwich). 2007 Jul;9(7):538-45
pubmed: 17617764
Expert Opin Drug Saf. 2020 Mar;19(3):257-267
pubmed: 32073914
Nutrients. 2019 Sep 02;11(9):
pubmed: 31480794
Sci Rep. 2019 May 22;9(1):7734
pubmed: 31118485
Eur J Med Chem. 2017 Jan 27;126:879-893
pubmed: 27988463
J Am Soc Nephrol. 2002 Aug;13(8):2145-51
pubmed: 12138148
Transplantation. 2017 Jan;101(1):32-44
pubmed: 27547870
Clin J Am Soc Nephrol. 2020 Feb 7;15(2):238-246
pubmed: 31896540
J Lipid Res. 2002 Aug;43(8):1170-80
pubmed: 12177161
Cell Death Dis. 2019 Aug 13;10(8):607
pubmed: 31406105
Am J Transplant. 2008 Dec;8(12):2600-6
pubmed: 18808405
Curr Opin Nephrol Hypertens. 1998 May;7(3):265-70
pubmed: 9617556
Int J Mol Sci. 2018 Dec 21;20(1):
pubmed: 30583483
Kidney Int. 2015 Feb;87(2):343-9
pubmed: 25229341
PLoS One. 2015 Nov 23;10(11):e0143405
pubmed: 26599323
Eur J Epidemiol. 2019 Sep;34(9):879-888
pubmed: 31025238
Kidney Int. 2020 Nov;98(5):1149-1159
pubmed: 32650020
N Engl J Med. 2003 Dec 11;349(24):2326-33
pubmed: 14668458
PLoS One. 2018 Dec 14;13(12):e0209156
pubmed: 30550582
N Engl J Med. 2002 Aug 15;347(7):488-96
pubmed: 12181403
Expert Rev Clin Immunol. 2014 Feb;10(2):295-305
pubmed: 24377908
Transpl Int. 2010 Nov;23(11):1126-34
pubmed: 20525020
Am J Kidney Dis. 2004 Jun;43(6):1071-81
pubmed: 15168388
Nutrients. 2020 Jul 27;12(8):
pubmed: 32726990
Clin Biochem. 2022 Mar;101:9-15
pubmed: 34890583
Transplantation. 2009 Jul 15;88(1):62-8
pubmed: 19584682
Am J Kidney Dis. 2007 Nov;50(5):830-3
pubmed: 17954297
Am J Kidney Dis. 2017 Dec;70(6):762-769
pubmed: 28801121
N Engl J Med. 2019 Jun 13;380(24):2295-2306
pubmed: 30990260
Transpl Int. 2020 Aug;33(8):849-857
pubmed: 32337766
Endocrinol Metab Clin North Am. 2014 Mar;43(1):75-102
pubmed: 24582093
Hemodial Int. 2004 Apr 1;8(2):118-29
pubmed: 19379407
Transplantation. 2009 Nov 15;88(9):1088-94
pubmed: 19898204
Am J Nephrol. 2014;40(6):546-53
pubmed: 25613554
Br J Pharmacol. 2011 Jan;162(1):136-46
pubmed: 20825407
Kidney Int. 2015 Aug;88(2):262-75
pubmed: 25692954
Cochrane Database Syst Rev. 2010 Apr 14;(4):CD002967
pubmed: 20393934
J Nephrol. 2001 Nov-Dec;14 Suppl 4:S81-8
pubmed: 11798152
Am J Physiol Renal Physiol. 2001 Oct;281(4):F693-706
pubmed: 11553517
Transplantation. 2002 Aug 27;74(4):485-8
pubmed: 12352906
Front Immunol. 2019 Nov 27;10:2701
pubmed: 31827468
Semin Nephrol. 2005 Jul;25(4):252-60
pubmed: 16202698
Am J Transplant. 2019 Nov;19(11):3018-3034
pubmed: 31152476
Clin J Am Soc Nephrol. 2008 Jan;3(1):226-36
pubmed: 18003763
Clin Transplant. 2020 Apr;34(4):e13820
pubmed: 32034944
J Nephrol. 2020 Feb;33(1):69-82
pubmed: 31028549
Ren Fail. 2020 Nov 10;42(1):1192-1204
pubmed: 33256487
Diabetes. 2013 Aug;62(8):2674-82
pubmed: 23881200
Kidney Int. 2000 Sep;58(3):1285-92
pubmed: 10972692
J Clin Invest. 2012 Nov;122(11):4172-89
pubmed: 23093779
Kidney Int. 2005 Jul;68(1):237-45
pubmed: 15954913
Transplantation. 2002 Mar 15;73(5):775-82
pubmed: 11907427
Can J Cardiol. 2020 May;36(5):635-647
pubmed: 32389337
Lipids Health Dis. 2019 Feb 12;18(1):49
pubmed: 30755212
Prog Cardiovasc Dis. 2015 Jul-Aug;58(1):50-60
pubmed: 25940230
Kidney Int. 2000 Dec;58(6):2597
pubmed: 11115100
Cell Mol Immunol. 2020 Mar;17(3):237-246
pubmed: 30948792
Semin Nephrol. 2017 Jan;37(1):54-65
pubmed: 28153195
Curr Opin Urol. 2002 Mar;12(2):125-30
pubmed: 11859258
Am J Transplant. 2006 Feb;6(2):429-33
pubmed: 16426332
Curr Opin Nephrol Hypertens. 2010 Jul;19(4):393-402
pubmed: 20489613
Int J Mol Sci. 2017 Apr 30;18(5):
pubmed: 28468297
Diabetes Care. 2012 Jan;35(1):99-104
pubmed: 22028277
Transplantation. 2012 Jan 15;93(1):41-6
pubmed: 22094957
BMJ Open. 2015 Aug 10;5(8):e008222
pubmed: 26260349
Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F433-45
pubmed: 26697982
Clin J Am Soc Nephrol. 2009 Feb;4(2):481-508
pubmed: 19218475
Transplantation. 2010 Mar 15;89(5):573-9
pubmed: 19997058
Value Health. 2020 Dec;23(12):1561-1569
pubmed: 33248511
Clin Transplant. 2009 Sep-Oct;23(5):628-36
pubmed: 19563484
Med Sci Sports Exerc. 2019 Jun;51(6):1154-1161
pubmed: 30629045
J Nephrol. 2021 Aug;34(4):1091-1125
pubmed: 33559850
Am J Kidney Dis. 2010 May;55(5):907-15
pubmed: 20176427
Curr Diabetes Rev. 2020;16(6):580-585
pubmed: 30907326
Immunol Rev. 2014 Mar;258(1):132-44
pubmed: 24517430
Lancet. 2019 Jul 13;394(10193):131-138
pubmed: 31189509
Diabetes Ther. 2020 Apr;11(4):987-994
pubmed: 32072430
Am J Kidney Dis. 2010 Jan;55(1):132-40
pubmed: 19932540
Transplantation. 2004 Mar 15;77(5):769-76
pubmed: 15021846
Kidney Int Rep. 2020 Dec 13;6(3):727-736
pubmed: 33732987
Transplant Proc. 1998 Aug;30(5):2039-42
pubmed: 9723383
N Engl J Med. 2016 Jul 28;375(4):311-22
pubmed: 27295427
Am J Transplant. 2005 Oct;5(10):2410-6
pubmed: 16162189
PLoS One. 2017 Jan 20;12(1):e0170393
pubmed: 28107415
Transpl Int. 2011 Jun;24(6):523-33
pubmed: 21382101
Am J Kidney Dis. 2011 Mar;57(3):466-75
pubmed: 21257243
Nat Rev Rheumatol. 2016 Apr;12(4):235-42
pubmed: 26416594
J Am Soc Nephrol. 2018 Jul;29(7):1960-1969
pubmed: 29789431
Ther Drug Monit. 2020 Oct;42(5):665-670
pubmed: 32520841
Kidney Int. 2008 Feb;73(4):391-8
pubmed: 18094682
Kidney Int. 2000 Sep;58(3):1311-7
pubmed: 10972695
J Cell Mol Med. 2017 Jul;21(7):1248-1259
pubmed: 28097825
Ther Adv Chronic Dis. 2018 Jun 13;9(9):179-190
pubmed: 30181847
Transplantation. 2008 Jan 27;85(2):209-16
pubmed: 18212625
Urol J. 2005 Winter;2(1):36-9
pubmed: 17629894
Pediatr Transplant. 2004 Oct;8(5):421-5
pubmed: 15367274
Am J Kidney Dis. 1994 Mar;23(3):471-5
pubmed: 8128953
Ann Intern Med. 1980 Dec;93(6):817-21
pubmed: 7447188
Am J Cardiol. 2009 Mar 15;103(6):867-71
pubmed: 19268747
Science. 2012 Mar 30;335(6076):1638-43
pubmed: 22461615
Nephron. 2018;138(4):261-274
pubmed: 29241197
Kidney Int. 2002 Jul;62(1):346-7
pubmed: 12081597
Am J Nephrol. 2011;33(4):352-7
pubmed: 21430373
Clin Nutr. 2006 Apr;25(2):295-310
pubmed: 16697495
Am J Kidney Dis. 2020 Sep;76(3 Suppl 1):S1-S107
pubmed: 32829751
Expert Opin Drug Saf. 2015 Feb;14(2):207-18
pubmed: 25496749
Transplant Rev (Orlando). 2014 Oct;28(4):188-92
pubmed: 25154797
Biomed Res Int. 2014;2014:406960
pubmed: 25136585
Clin Pharmacokinet. 2017 May;56(5):459-475
pubmed: 27753003
Semin Nephrol. 2007 Mar;27(2):195-207
pubmed: 17418688
PLoS One. 2015 Jan 05;10(1):e0116207
pubmed: 25559848
J Clin Invest. 2012 Nov;122(11):3854-7
pubmed: 23093783
Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F471-80
pubmed: 23283992
Transplantation. 2001 Jun 27;71(12):1752-7
pubmed: 11455254
Nutrients. 2019 Aug 05;11(8):
pubmed: 31387226
J Am Soc Nephrol. 2012 Feb;23(2):360-8
pubmed: 22193388
Clin Immunol. 2007 Apr;123(1):7-13
pubmed: 17064966