The Role of the Pharmacist in Selecting the Best Choice of Medication Formulation in Dysphagic Patients.

compounding pharmacist dysphagic patients hospital pharmacy off-label prescriptions patient safety solid oral formulations

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
12 Aug 2022
Historique:
received: 22 07 2022
revised: 03 08 2022
accepted: 08 08 2022
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 27 8 2022
Statut: epublish

Résumé

Usually, the administration of drugs by feeding tube in dysphagic patients involves handling of marketing licenses outside their term, due to the lack of suitable formulations. This circumstance has put health professionals in the dilemma of choosing the formulation whose manipulation possibly does not alter the effectiveness of the drug. In this regard, a practical guide providing indications on the prescription, handling, and administration of drugs through enteral feeding tube could be of paramount utility. For this purpose, we have considered the 1047 solid oral pharmaceutical forms included in the formulary of San Paolo Hospital (Savona, Italy). From our analysis, it emerges that 95% of medicinal products are worryingly used off-label and 40% have to be managed by the hospital pharmacists without having suitable indications by either the manufacturers or by literature studies. To fill this gap, we have compiled a detailed table containing missing indications derived from pharmacist expertise and evidence-based practices, with the aim that the sharing of our procedures will contribute to make uniform pharmacological therapies from one hospital to another. This study will allow doctors to have easy access to information on drugs that can be prescribed and nurses to become familiar only with the pharmaceutical forms that can be administered.

Identifiants

pubmed: 36013259
pii: jpm12081307
doi: 10.3390/jpm12081307
pmc: PMC9410388
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Guendalina Zuccari (G)

Department of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.

Sara Macis (S)

Hospital Pharmacy, Department Technical Health, San Paolo Hospital, Via Genova, 17100 Savona, Italy.

Silvana Alfei (S)

Department of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.

Leonardo Marchitto (L)

Department of Sciences for the Quality of Life, University of Bologna, Corso D'Augusto 237, 47921 Rimini, Italy.

Eleonora Russo (E)

Department of Pharmacy, University of Genoa, Viale Cembrano, 16148 Genoa, Italy.

Classifications MeSH