Dyslexia associated gene

KIAA0319 NPCs cell cycle differentiation hESCs

Journal

Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250

Informations de publication

Date de publication:
2022
Historique:
received: 12 06 2022
accepted: 07 07 2022
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 27 8 2022
Statut: epublish

Résumé

Dyslexia, also known as reading disability, is defined as difficulty processing written language in individuals with normal intellectual capacity and educational opportunity. The prevalence of dyslexia is between 5 and 17%, and the heritability ranges from 44 to 75%. Genetic linkage analysis and association studies have identified several genes and regulatory elements linked to dyslexia and reading ability. However, their functions and molecular mechanisms are not well understood. Prominent among these is

Identifiants

pubmed: 36016658
doi: 10.3389/fcell.2022.967147
pii: 967147
pmc: PMC9395643
doi:

Types de publication

Journal Article

Langues

eng

Pagination

967147

Subventions

Organisme : NICHD NIH HHS
ID : P50 HD027802
Pays : United States
Organisme : NHGRI NIH HHS
ID : R01 HG010171
Pays : United States
Organisme : NICHD NIH HHS
ID : R15 HD087937
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States

Informations de copyright

Copyright © 2022 Paniagua, Cakir, Hu, Kiral, Tanaka, Xiang, Patterson, Gruen and Park.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Steven Paniagua (S)

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.

Bilal Cakir (B)

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.

Yue Hu (Y)

Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States.

Ferdi Ridvan Kiral (FR)

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.

Yoshiaki Tanaka (Y)

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.
Department of Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, QC, Canada.

Yangfei Xiang (Y)

School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

Benjamin Patterson (B)

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.

Jeffrey R Gruen (JR)

Departments of Pediatrics and of Genetics, Yale School of Medicine, New Haven, CT, United States.

In-Hyun Park (IH)

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, United States.

Classifications MeSH