Transcriptional regulation of the thymus master regulator


Journal

Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624

Informations de publication

Date de publication:
26 08 2022
Historique:
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 31 8 2022
Statut: ppublish

Résumé

FOXN1 is a transcription factor critical for the development of both thymic epithelial cell (TEC) and hair follicle cell (HFC) compartments. However, mechanisms controlling its expression remain poorly understood. To address this question, we performed thorough analyses of the evolutionary conservation and chromatin status of the

Identifiants

pubmed: 36026441
doi: 10.1126/sciimmunol.abn8144
doi:

Substances chimiques

RNA-Binding Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabn8144

Auteurs

Noam Kadouri (N)

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

Tal Givony (T)

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

Shir Nevo (S)

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

Joschka Hey (J)

Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ruprecht Karl University of Heidelberg, Heidelberg, Germany.

Shifra Ben Dor (S)

Bioinformatics Unit, Weizmann Institute of Science, Rehovot, Israel.

Golda Damari (G)

Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.

Bareket Dassa (B)

Bioinformatics Unit, Weizmann Institute of Science, Rehovot, Israel.

Jan Dobes (J)

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

Dieter Weichenhan (D)

Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Marion Bähr (M)

Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Michelle Paulsen (M)

Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Department of Translational Pulmonology, University of Heidelberg, Heidelberg, Germany.

Rebecca Haffner-Krausz (R)

Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.

Marcus A Mall (MA)

Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Department of Translational Pulmonology, University of Heidelberg, Heidelberg, Germany.
Charité-Universitätsmedizin Berlin, Berlin, Germany.

Christoph Plass (C)

Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Yael Goldfarb (Y)

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

Jakub Abramson (J)

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

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Classifications MeSH