Psychological distress and adherence to anti-retroviral therapy or pre-exposure prophylaxis regimens among Urban Black gay and bisexual men (MSM).

Anti-HIV Agents / therapeutic use HIV Infections / drug therapy Homosexuality, Male / psychology Humans Male Medication Adherence Pre-Exposure Prophylaxis Prospective Studies Psychological Distress Sexual and Gender Minorities
ART MSM PrEP adherence to care psychological distress

Journal

International journal of STD & AIDS
ISSN: 1758-1052
Titre abrégé: Int J STD AIDS
Pays: England
ID NLM: 9007917

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 28 8 2022
medline: 13 10 2022
entrez: 27 8 2022
Statut: ppublish

Résumé

Urban Black gay, and bisexual men (MSM) bear a disproportionate burden of HIV in the U.S. Mental health is a barrier to adherence to both antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP). The objective was to determine the association between psychological distress and ART or PrEP adherence among urban Black MSM. Using data from a four-year prospective cohort study, adherence to ART was defined as > 95% and PrEP was defined as > 80% of doses taken in the past 30 days. Psychological distress measures included difficulty sleeping; feeling anxious; suicidality; feeling sad or depressed; feeling sick, ill, or not well in the past 3 months; high (vs. low) overall psychological distress was classified as above the median value. Associations were examined using Chi-square, Fisher's exact tests, and logistic regression. Among 165 Black MSM, 44.2% (73) reported high psychological distress. 65.3% (47/72) of participants living with HIV and 39.8% (37/93) of HIV negative participants were ART or PrEP adherent, respectively. Education was significantly associated with PrEP adherence ( Increased psychological distress was significantly associated with ART nonadherence and may represent an important barrier to viral suppression.

Sections du résumé

BACKGROUND
Urban Black gay, and bisexual men (MSM) bear a disproportionate burden of HIV in the U.S. Mental health is a barrier to adherence to both antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP). The objective was to determine the association between psychological distress and ART or PrEP adherence among urban Black MSM.
METHODS
Using data from a four-year prospective cohort study, adherence to ART was defined as > 95% and PrEP was defined as > 80% of doses taken in the past 30 days. Psychological distress measures included difficulty sleeping; feeling anxious; suicidality; feeling sad or depressed; feeling sick, ill, or not well in the past 3 months; high (vs. low) overall psychological distress was classified as above the median value. Associations were examined using Chi-square, Fisher's exact tests, and logistic regression.
RESULTS
Among 165 Black MSM, 44.2% (73) reported high psychological distress. 65.3% (47/72) of participants living with HIV and 39.8% (37/93) of HIV negative participants were ART or PrEP adherent, respectively. Education was significantly associated with PrEP adherence (
CONCLUSIONS
Increased psychological distress was significantly associated with ART nonadherence and may represent an important barrier to viral suppression.

Identifiants

DOI: 10.1177/09564624221123466 PMID: 36028928
pubmed: 36028928
doi: 10.1177/09564624221123466
doi:

Substances chimiques

Anti-HIV Agents 0

Types de publication

Journal Article Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1005-1012

Auteurs

Valeria Jimenez (V)

Krieger School of Arts and Sciences, 1466Johns Hopkins University, Baltimore, MD, USA.

Nicole Thornton (N)

Center for Child and Community Health Research (CCHR), Department of Pediatrics, 1500Johns Hopkins School of Medicine, Baltimore, MD, USA.

Carla Tilchin (C)

Center for Child and Community Health Research (CCHR), Department of Pediatrics, 1500Johns Hopkins School of Medicine, Baltimore, MD, USA.
Department of Health, Behavior, and Society, 1500Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Khalil G Ghanem (KG)

Division of Infectious Diseases, 1500Johns Hopkins School of Medicine, Baltimore, MD, USA.

Sebastian Ruhs (S)

Chase Brexton, Baltimore, MD, USA.

Matthew M Hamill (MM)

Division of Infectious Diseases, 1500Johns Hopkins School of Medicine, Baltimore, MD, USA.
STI/HIV Program, 217334Baltimore City Health Department, Baltimore, MD, USA.

Anne Rompalo (A)

Division of Infectious Diseases, 1500Johns Hopkins School of Medicine, Baltimore, MD, USA.

Jacky M Jennings (JM)

Center for Child and Community Health Research (CCHR), Department of Pediatrics, 1500Johns Hopkins School of Medicine, Baltimore, MD, USA.
Department of Health, Behavior, and Society, 1500Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Department of Epidemiology, 1500Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
ORCID: 0000-0002-3789-5122

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Antirétroviraux › Agents antiVIH › Psychological distress and adherence to...
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Psychological distress and adherence to...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Sexualité › Homosexualité › Homosexualité masculine › Psychological distress and adherence to...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Psychological distress and adherence to...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Prestations des soins de santé › Attitude envers la santé › Adhésion et observance thérapeutiques › Acceptation des soins par les patients › Observance par le patient › Adhésion au traitement médicamenteux › Psychological distress and adherence to...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Prophylaxie pré-exposition › Psychological distress and adherence to...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Psychological distress and adherence to...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Émotions › Détresse psychologique › Psychological distress and adherence to...
questionsmedicales.fr › Personnes › Disparités en matière de santé, minorités et populations vulnérables › Minorités sexuelles › Psychological distress and adherence to...