Oral Bacille Calmette-Guérin (BCG) vaccination induces long-term potentiation of memory immune response to Ovalbumin airway challenge in mice.

Animals BCG Vaccine / pharmacology Forkhead Transcription Factors Immunity Immunoglobulin E Immunoglobulin G Interferon-gamma Interleukin-17 Long-Term Potentiation Mice Ovalbumin Vaccination / methods
BCG IFN-γ Tregs foxp3 trained immunity γδ T cells

Journal

Immunology letters
ISSN: 1879-0542
Titre abrégé: Immunol Lett
Pays: Netherlands
ID NLM: 7910006

Informations de publication

Date de publication:
09 2022
Historique:
received: 30 03 2022
revised: 09 08 2022
accepted: 24 08 2022
pubmed: 29 8 2022
medline: 28 9 2022
entrez: 28 8 2022
Statut: ppublish

Résumé

The Bacille Calmette-Guérin (BCG) is a potent immunomodulator. It was initially used by oral administration, but it is mostly used subcutaneously nowadays. This study shows that oral BCG vaccination modifies the immune response to a second non-related antigen (Ovalbumin) systemic immunization. Airway Ovalbumin challenge six months after the systemic intraperitoneal immunization resulted in a potent γδ

Identifiants

DOI: 10.1016/j.imlet.2022.08.004 PMID: 36031026
pubmed: 36031026
pii: S0165-2478(22)00115-8
doi: 10.1016/j.imlet.2022.08.004
pii:
doi:

Substances chimiques

BCG Vaccine 0
Forkhead Transcription Factors 0
Immunoglobulin G 0
Interleukin-17 0
Immunoglobulin E 37341-29-0
Interferon-gamma 82115-62-6
Ovalbumin 9006-59-1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

43-52

Informations de copyright

Copyright © 2022. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interests The authors declare no conflict of interest.

Auteurs

Andreza Hammes (A)

Laboratory of Basical and Clinical Immunology, Petrópolis Medical School, UNIFASE, Petrópolis, RJ, Brazil.

Fabíola Cardillo (F)

Laboratory of Molecular and Structural Pathology, Gonçalo Moniz Institute, Fiocruz, Salvador, BA, Brazil.

Rodolfo Frota (R)

Laboratory of Basical and Clinical Immunology, Petrópolis Medical School, UNIFASE, Petrópolis, RJ, Brazil.

Rosa Teixeira de Pinho (RT)

Laboratory of Clinical Immunology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, RJ, Brazil.

José Mengel (J)

Laboratory of Basical and Clinical Immunology, Petrópolis Medical School, UNIFASE, Petrópolis, RJ, Brazil; Laboratory of Clinical Immunology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, RJ, Brazil.. Electronic address: jomengel@ioc.fiocruz.br.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antibactériens › Vaccins antituberculeux › Vaccin BCG › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif hélice ailée › Facteurs de transcription Forkhead › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline E › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline G › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Lymphokines › Facteurs d'activation des macrophages › Interféron gamma › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-17 › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Plasticité neuronale › Potentialisation à long terme › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Ovalbumine › Oral Bacille Calmette-Guérin (BCG) vaccination...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Vaccination › Oral Bacille Calmette-Guérin (BCG) vaccination...