High level of γH2AX phosphorylation in the cord-blood cells of large-for-gestational-age (LGA) newborns.
Cord-blood cells
DSB
GH2AX assay
Newborns
Oxidative damage
Journal
Mutation research. Genetic toxicology and environmental mutagenesis
ISSN: 1879-3592
Titre abrégé: Mutat Res Genet Toxicol Environ Mutagen
Pays: Netherlands
ID NLM: 101632149
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
14
04
2022
revised:
05
07
2022
accepted:
06
07
2022
entrez:
28
8
2022
pubmed:
29
8
2022
medline:
31
8
2022
Statut:
ppublish
Résumé
Newborns can experience adverse effects as a consequence of maternal or in utero exposure, altered growth of the fetus, or placental dysfunctions. Accurate characterization of gestational age allows monitoring of fetal growth, identification of deviations from the normal growth trajectory, and classification of babies as adapted, small, or large for gestational age (AGA, SGA, or LGA). The aim of this work was to evaluate nuclear and oxidative damage in umbilical cord-blood cells of newborns (sampled at birth), by applying the γH2AX assay and the fluorescent probe BODIPY
Identifiants
pubmed: 36031337
pii: S1383-5718(22)00088-2
doi: 10.1016/j.mrgentox.2022.503526
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
503526Informations de copyright
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