Perspectives on the Immune System in Sepsis.
Journal
Maedica
ISSN: 1841-9038
Titre abrégé: Maedica (Bucur)
Pays: Romania
ID NLM: 101526930
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
entrez:
29
8
2022
pubmed:
30
8
2022
medline:
30
8
2022
Statut:
ppublish
Résumé
Beyond the modifications shown by the biochemistry labs, profound and ample modifications are seen in septic patients at a molecular level stemming from DNA translation and gene expression, manifested as unique profiles of mRNA (messenger), as well as non-coding, functional RNAs: miRNA (micro) and lncRNAs (long non-coding). Counteracting these modifications requires treatment with pleiotropic molecules and/or combination of molecules and opens the possibility of future treatments with arrays of siRNAs and/or specific panels of small molecules tailored for each patient subpopulation.
Identifiants
pubmed: 36032596
doi: 10.26574/maedica.2022.17.2.395
pmc: PMC9375866
doi:
Types de publication
Editorial
Langues
eng
Pagination
395-403Références
JCI Insight. 2019 May 2;4(9):
pubmed: 31045578
Nat Rev Immunol. 2013 Dec;13(12):862-74
pubmed: 24232462
J Immunol. 2021 Oct 1;207(7):1871-1881
pubmed: 34479943
Crit Care Med. 2007 Sep;35(9 Suppl):S591-5
pubmed: 17713414
Medicine (Baltimore). 2018 Jul;97(27):e11352
pubmed: 29979415
PLoS One. 2013;8(3):e60501
pubmed: 23544148
Crit Care Resusc. 2017 Sep;19(3):205-213
pubmed: 28866970
Elife. 2021 Oct 15;10:
pubmed: 34652273
Anticancer Res. 2014 Oct;34(10):5337-50
pubmed: 25275027
Crit Care Med. 2009 May;37(5):1670-7
pubmed: 19325467
Physiol Rev. 2013 Jul;93(3):1247-88
pubmed: 23899564
Cell Mol Biol (Noisy-le-grand). 2020 Jul 31;66(5):131-136
pubmed: 33040826
Crit Care. 2021 Mar 19;25(1):114
pubmed: 33741010
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
Exp Cell Res. 2021 Sep 15;406(2):112756
pubmed: 34384779
Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18484-9
pubmed: 19020089
Oncotarget. 2017 Oct 10;8(53):91765-91778
pubmed: 29207683
J Immunol. 2001 Jun 1;166(11):6952-63
pubmed: 11359857
Crit Care Med. 2011 Jun;39(6):1351-8
pubmed: 21378552
Crit Rev Immunol. 2013;33(1):23-40
pubmed: 23510024
Int J Mol Med. 2020 Aug;46(2):489-508
pubmed: 32626922
Lancet. 2004 Aug 7-13;364(9433):545-8
pubmed: 15302200
Crit Care Med. 2003 Apr;31(4):1250-6
pubmed: 12682500
Crit Care Med. 2021 Oct 1;49(10):1664-1673
pubmed: 34166284
Cell. 1989 Jul 28;58(2):227-9
pubmed: 2665943
Sci Transl Med. 2013 Jul 24;5(195):195ra95
pubmed: 23884467
Exp Ther Med. 2020 Jun;19(6):3521-3530
pubmed: 32346413
Ann Clin Biochem. 2018 Jan;55(1):143-148
pubmed: 28135842
PeerJ. 2020 Jul 21;8:e9559
pubmed: 32742812
Front Immunol. 2021 Sep 22;12:722004
pubmed: 34630395
Mol Cell Biochem. 2016 Oct;421(1-2):157-68
pubmed: 27565812
Crit Care. 2007;11(2):R38
pubmed: 17362525
BMC Emerg Med. 2021 Jan 7;21(1):2
pubmed: 33413139
Crit Care Med. 1999 Jul;27(7):1230-51
pubmed: 10446814
Br J Nutr. 2012 May;107(10):1458-65
pubmed: 22129964
Oncotarget. 2017 Dec 28;9(13):10934-10944
pubmed: 29541387
Int Immunopharmacol. 2019 Oct;75:105731
pubmed: 31344555
J Intensive Care. 2020 Nov 2;8(1):84
pubmed: 33292630
Nature. 2012 Sep 6;489(7414):57-74
pubmed: 22955616
PLoS One. 2017 Jul 3;12(7):e0180554
pubmed: 28671974
Elife. 2013 Jul 23;2:e00762
pubmed: 23898399
J Crit Care. 2018 Feb;43:139-142
pubmed: 28898742
Chin Med J (Engl). 2017 May 20;130(10):1218-1225
pubmed: 28485323
Biomed Res Int. 2016;2016:3624730
pubmed: 27366743
Nature. 1998 Jan 22;391(6665):410-3
pubmed: 9450761
Crit Rev Immunol. 2016;36(1):57-74
pubmed: 27480902
J Clin Lab Anal. 2020 Feb;34(2):e23036
pubmed: 32077163
J Cell Physiol. 2019 Feb;234(2):1030-1043
pubmed: 30146762
Inflamm Res. 2017 Jul;66(7):553-569
pubmed: 28258291
Ann Intensive Care. 2019 May 20;9(1):58
pubmed: 31111241
Hum Cell. 2021 Sep;34(5):1335-1345
pubmed: 33978928
Int Immunopharmacol. 2017 Nov;52:61-69
pubmed: 28863323
BMJ Open. 2019 Apr 23;9(4):e026527
pubmed: 31015272
Crit Care Explor. 2021 Oct 14;3(10):e0554
pubmed: 34671746
JAMA. 2019 Oct 1;322(13):1261-1270
pubmed: 31573637
J Immunol. 2013 Mar 1;190(5):1991-2000
pubmed: 23355736
PLoS One. 2012;7(7):e38400
pubmed: 22911680
Leuk Lymphoma. 2011 Dec;52(12):2349-55
pubmed: 21756036
J Clin Med. 2020 Jun 01;9(6):
pubmed: 32492832
Am J Respir Crit Care Med. 2015 Feb 1;191(3):309-15
pubmed: 25489881
Virulence. 2014 Jan 1;5(1):36-44
pubmed: 23774844
Crit Care. 2020 Jun 5;24(1):287
pubmed: 32503670
Crit Care Clin. 2020 Jan;36(1):23-40
pubmed: 31733680
Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4898-4907
pubmed: 31210324
J Leukoc Biol. 2014 Nov;96(5):767-77
pubmed: 24791959
BMC Pulm Med. 2019 May 14;19(1):93
pubmed: 31088429
J Pers Med. 2020 Dec 07;10(4):
pubmed: 33297498
Nutrients. 2019 Dec 05;11(12):
pubmed: 31817439
Biomolecules. 2020 Aug 13;10(8):
pubmed: 32823646
Antioxid Redox Signal. 2013 Dec 10;19(17):2054-67
pubmed: 23249337
Neuropathol Appl Neurobiol. 2019 Oct;45(6):538-556
pubmed: 30636336
Front Med (Lausanne). 2021 Nov 05;8:775511
pubmed: 34805235
J Biol Chem. 2017 Jul 28;292(30):12375-12382
pubmed: 28615453