Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients.

Kidney transplantation Nephron-sparing treatment Renal cancer Small renal mass

Journal

Asian journal of urology
ISSN: 2214-3882
Titre abrégé: Asian J Urol
Pays: Singapore
ID NLM: 101699720

Informations de publication

Date de publication:
Jul 2022
Historique:
received: 08 12 2021
revised: 24 03 2022
accepted: 19 04 2022
entrez: 29 8 2022
pubmed: 30 8 2022
medline: 30 8 2022
Statut: ppublish

Résumé

Kidney transplantation is the best replacement treatment for the end-stage renal disease. Currently, the imbalance between the number of patients on a transplant list and the number of organs available constitutes the crucial limitation of this approach. To expand the pool of organs amenable for transplantation, kidneys coming from older patients have been employed; however, the combination of these organs in conjunction with the chronic use of immunosuppressive therapy increases the risk of incidence of graft small renal tumors. This narrative review aims to provide the state of the art on the clinical impact and management of incidentally diagnosed small renal tumors in either donors or recipients. According to the most updated evidence, the use of grafts with a small renal mass, after bench table tumor excision, may be considered a safe option for high-risk patients in hemodialysis. On the other hand, an early small renal mass finding on periodic ultrasound-evaluation in the graft should allow to perform a conservative treatment in order to preserve renal function. Finally, in case of a renal tumor in native kidney, a radical nephrectomy is usually recommended.

Identifiants

pubmed: 36035353
doi: 10.1016/j.ajur.2022.06.001
pii: S2214-3882(22)00039-X
pmc: PMC9399547
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

208-214

Informations de copyright

© 2022 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Alberto Piana (A)

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.
Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.

Iulia Andras (I)

Urology Department, Iuliu Hatieganu University of Medicine and Pharmacy and Municipal Hospital, Cluj-Napoca, Romania.

Pietro Diana (P)

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.

Paolo Verri (P)

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.
Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.

Andrea Gallioli (A)

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.

Riccardo Campi (R)

Unit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Thomas Prudhomme (T)

Department of Urology and Kidney Transplantation, Toulouse University Hospital, Toulouse, France.

Vital Hevia (V)

Hospital Universitario Ramon y Cajal. Alcala University, Instituto Ramon y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

Romain Boissier (R)

Aix-Marseille université, service de chirurgie urologique et de transplantation rénale, CHU Conception, AP-HM, Marseille, France.

Alberto Breda (A)

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.

Angelo Territo (A)

Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain.

Classifications MeSH