The effects of a new protocol on blood loss in total knee arthroplasty.
acid tranexamic protocol
blood loss
total knee arthroplasty
transfusion
Journal
Orthopedic reviews
ISSN: 2035-8164
Titre abrégé: Orthop Rev (Pavia)
Pays: United States
ID NLM: 101524779
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
29
8
2022
pubmed:
30
8
2022
medline:
30
8
2022
Statut:
epublish
Résumé
The aim of study was to evaluate the efficacy of blood loss prevention with Tranexamic acid in patients undergoing total knee arthroplasty (TKA). The Authors defined a new protocol that foresees the use of Tranexamic acid both pre-intra and post-operatively. Seventy patients indicated for TKA were enrolled. Thirty-five patients (control group) followed standard protocol without Tranexamic acid and the other 35 patients (study group) followed standard protocol with Tranexamic acid. We analyzed the values of hemoglobin (Hb), hematocrit (HCT) and red blood cells (RBCs) both pre-operatively (T0) and post-operatively: immediately after surgery (T1), at one day (T2) and three days post-op (T3). We observed statistical differences at T0 and T3 regarding the Hb, HT and RBCs value between the two groups. Moreover, 11.4% in the study and 28.5% in the control group required blood transfusion. No thrombotic or thrombo-embolic events were reported. We conclude that Tranexamic acid use, as in our protocol, reduces postoperative bleeding in primary knee arthroplasty, with the absence of thrombo-embolic events.
Identifiants
pubmed: 36035591
doi: 10.52965/001c.37625
pii: 37625
pmc: PMC9404250
doi:
Types de publication
Journal Article
Langues
eng
Pagination
37625Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest regarding the publication of this paper.
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