East Coast fever, a neglected tropical disease with an outdated vaccine approach?

Acaricides Animals Cattle Humans Protozoan Vaccines Theileria parva Theileriasis / parasitology
Theileria parva cellular immunity drug resistance glycobiology infection and treatment method (ITM) protein modelling

Journal

Trends in parasitology
ISSN: 1471-5007
Titre abrégé: Trends Parasitol
Pays: England
ID NLM: 100966034

Informations de publication

Date de publication:
11 2022
Historique:
received: 04 07 2022
revised: 04 08 2022
accepted: 11 08 2022
pubmed: 31 8 2022
medline: 18 10 2022
entrez: 30 8 2022
Statut: ppublish

Résumé

Since its discovery, bovine theileriosis has caused major socioeconomic losses in sub-Saharan Africa. Acaricide resistance of the intermediate host, paucity of therapeutics, and lack of sufficiently cross-protective vaccines increase the risk of parasite spread due to global warming. Here, we highlight three important areas that require investigation to develop next-generation vaccines.

Identifiants

DOI: 10.1016/j.pt.2022.08.006 PMID: 36041933
pubmed: 36041933
pii: S1471-4922(22)00183-0
doi: 10.1016/j.pt.2022.08.006
pii:
doi:

Substances chimiques

Acaricides 0
Protozoan Vaccines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

930-932

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors have no competing interests to declare.

Auteurs

Jeannine Kolakowski (J)

Centre for Vaccinology and Regenerative Medicine, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, London, UK.

Tim Connelley (T)

Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Edinburgh, UK.

Petra Lukacik (P)

Department of Life Science, Diamond Light Source Ltd, Harwell, UK.

Mark Pfuhl (M)

Department of Muscle Biology, King's College London, London, UK.

Dirk Werling (D)

Centre for Vaccinology and Regenerative Medicine, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, London, UK. Electronic address: dwerling@rvc.ac.uk.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Pesticides › Acaricides › East Coast fever, a neglected tropical disease...
questionsmedicales.fr › Eucaryotes › Animaux › East Coast fever, a neglected tropical disease...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Ruminants › Bovins › East Coast fever, a neglected tropical disease...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › East Coast fever, a neglected tropical disease...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antiprotozoaires › East Coast fever, a neglected tropical disease...
questionsmedicales.fr › Eucaryotes › Alveolata › Apicomplexa › Piroplasmia › Piroplasmida › Theileria › Theileria parva › East Coast fever, a neglected tropical disease...
questionsmedicales.fr › Maladies de l'animal › Parasitoses animales › Protozooses animales › Theilériose › East Coast fever, a neglected tropical disease...