Identification of protein biomarkers of attenuation and immunogenicity of centrin or p27 gene deleted live vaccine candidates of Leishmania against visceral leishmaniasis.
Attenuation
Biomarker
Centrin
Leishmania
Proteomics
Vaccine
Journal
Parasitology international
ISSN: 1873-0329
Titre abrégé: Parasitol Int
Pays: Netherlands
ID NLM: 9708549
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
received:
17
12
2021
revised:
08
07
2022
accepted:
23
08
2022
pubmed:
2
9
2022
medline:
23
11
2022
entrez:
1
9
2022
Statut:
ppublish
Résumé
Currently, no licensed vaccine is available for human visceral leishmaniasis (VL), a fatal disease caused by the protozoan parasite Leishmania donovani. Two of our live attenuated L. donovani vaccine candidates, either deleted for Centrin1 (LdCen1
Identifiants
pubmed: 36049661
pii: S1383-5769(22)00125-8
doi: 10.1016/j.parint.2022.102661
pii:
doi:
Substances chimiques
Trimethoprim, Sulfamethoxazole Drug Combination
8064-90-2
Biomarkers
0
Vaccines, Attenuated
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102661Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None of the authors has any conflict of interest to disclose.