Sex-bias in CD8


Journal

Clinical & translational immunology
ISSN: 2050-0068
Titre abrégé: Clin Transl Immunology
Pays: Australia
ID NLM: 101638268

Informations de publication

Date de publication:
2022
Historique:
received: 08 08 2022
revised: 11 08 2022
accepted: 11 08 2022
entrez: 2 9 2022
pubmed: 3 9 2022
medline: 3 9 2022
Statut: epublish

Résumé

This commentary article highlights two recently published studies, which for the first time revealed the immunological underpinnings of sex-bias in cancer incidence and mortality. These studies showed that the androgen receptor restrains anti-tumour immunity in males by repressing cytotoxic genes in CD8

Identifiants

pubmed: 36051310
doi: 10.1002/cti2.1414
pii: CTI21414
pmc: PMC9418121
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e1414

Informations de copyright

© 2022 The Authors. Clinical & Translational Immunology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Tabinda Hussain (T)

Olivia Newton-John Cancer Research Institute Heidelberg VIC Australia.
La Trobe University Bundoora VIC Australia.

Axel Kallies (A)

Department of Microbiology and Immunology University of Melbourne Melbourne VIC Australia.
Peter Doherty Institute for Infection and Immunity Melbourne VIC Australia.

Ajithkumar Vasanthakumar (A)

Olivia Newton-John Cancer Research Institute Heidelberg VIC Australia.
La Trobe University Bundoora VIC Australia.
Department of Microbiology and Immunology University of Melbourne Melbourne VIC Australia.

Classifications MeSH