European-Australasian consensus on the management of advanced gastric and gastro-oesophageal junction cancer: current practice and new directions.

antiangiogenesis chemotherapy gastric adenocarcinoma gastro-oesophageal junction immune checkpoint inhibitors refractory disease

Journal

Therapeutic advances in medical oncology
ISSN: 1758-8340
Titre abrégé: Ther Adv Med Oncol
Pays: England
ID NLM: 101510808

Informations de publication

Date de publication:
2022
Historique:
received: 05 04 2022
accepted: 25 07 2022
entrez: 2 9 2022
pubmed: 3 9 2022
medline: 3 9 2022
Statut: epublish

Résumé

Gastric carcinoma and gastro-oesophageal junction (GC/GEJ) carcinoma remain a significant global problem, with patients presenting with symptoms often found to have advanced or metastatic disease. Treatment options for these patients have broadened in recent years with new chemotherapy agents, agents targeting angiogenic pathways and the development of immune checkpoint inhibitors (ICIs). Most initial advances have occurred in the refractory setting, where it is important to balance treatment benefits

Identifiants

pubmed: 36051471
doi: 10.1177/17588359221118874
pii: 10.1177_17588359221118874
pmc: PMC9425884
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

17588359221118874

Informations de copyright

© The Author(s), 2022.

Déclaration de conflit d'intérêts

Competing Interests: All authors have no COI directly related to this work. BUT COI Statements from authors with industry unrelated to this work are as follows: Nick Pavlakis: Advisory Boards MSD, Merck, BMS, Takeda, Beigene, Astra Zeneca, Roche, Amgen, Novartis Speaking Honoraria Roche, Pierre-Faber Research Funding – to institution Bayer, Roche Christos Karapetis: Advisory Board Amgen, Astra Zeneca, Beigene, BMS, Eli Lilly, Eisai, Ipsen, Merck, MSD, Pierre Fabre, Roche, Takeda Timothy Price: Advisory Board MSD, Merck Serono, Pierre Fabre, BMS, Servier Radka Obermannova: Personal fee BMS, Merck, MSD, Servie Research support (to institution): Roche Florian Lordick: Honorari BMS, MSD, Roche, Astra Zeneca Lorraine Chantrill: Advisory Board Pierre Fabre, AstraZeneca, BMS, Merck

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Auteurs

Nick Pavlakis (N)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaDepartment of Medical Oncology, Royal North Shore Hospital, Sydney University, Reserve Road, St Leonards, Sydney, NSW 2065, AustraliaGenesis Care, North Shore Health Hub, St Leonards, NSW, Australia.

Gary Tincknell (G)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaIllawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia.

Lisi Elizabeth Lim (LE)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaBallarat Regional Integrated Cancer Centre, Ballarat, VIC, Australia.

Kei Muro (K)

Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.

Radka Obermannova (R)

Masaryk Memorial Cancer Institute, Brno, Czech Republic.

Sylvie Lorenzen (S)

Department of Hematology and Oncology, Technical University, Munich, Germany.

Yu Jo Chua (YJ)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaDepartment of Medical Oncology, Canberra Hospital.

Chris Jackson (C)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaDepartment of Medicine, Otago Medical School, University of Otago, Dunedin, New Zealand.

Christos Stelios Karapetis (CS)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaFlinders Medical Centre and Flinders University, Adelaide, SA, Australia.

Timothy Price (T)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaQueen Elizabeth Hospital, Adelaide, SA, Australia.

Lorraine Chantrill (L)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaIllawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia.

Eva Segelov (E)

The Australasian Gastrointestinal Trials Group (AGITG), Camperdown, NSW, AustraliaDepartment of Medical Oncology, Monash Health and Monash University, Clayton, VIC, Australia.

Florian Lordick (F)

University Cancer Centre, Leipzig University Medical Centre, Germany.

Classifications MeSH