Epidemiology and Financial Burden of Adult Chronic Hypoparathyroidism.
COMPLICATIONS
EPIDEMIOLOGY
FINANCIAL BURDEN
HYPOPARATHYROIDISM
PREVALENCE
Journal
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
ISSN: 1523-4681
Titre abrégé: J Bone Miner Res
Pays: United States
ID NLM: 8610640
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
revised:
29
07
2022
received:
04
02
2022
accepted:
07
08
2022
pubmed:
3
9
2022
medline:
22
12
2022
entrez:
2
9
2022
Statut:
ppublish
Résumé
Chronic hypoparathyroidism is characterized by low serum calcium, increased serum phosphorus, and inappropriately low or decreased serum parathyroid hormone. This rare disorder is associated with a variety of complications. The prevalence, incidence, mortality, financial burden, and epidemiology of complications of this disorder are not well understood. This narrative review summarizes current information on the epidemiology and complications of chronic hypoparathyroidism. The reported prevalence of chronic hypoparathyroidism ranges from 6.4-37/100,000, and the incidence is reported to be 0.8-2.3/100,000/year. Mortality is not increased in studies from Denmark or South Korea but was increased in studies from Scotland and Sweden. The financial burden of this disorder is substantial because of increased health care resource utilization in two studies but not well quantitated. Recognized complications include hypercalciuria, nephrocalcinosis, kidney stones, and chronic kidney disease; low bone turnover and possibly upper extremity fractures; cardiac and vascular calcifications; basal ganglia calcifications, cataracts, infections, neuropsychiatric complications, and difficulties with pregnancy. This review concludes that chronic hypoparathyroidism is a rare disorder associated with significant morbidity that may not increase overall mortality but is associated with a substantial financial burden. © 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).
Identifiants
pubmed: 36054571
doi: 10.1002/jbmr.4675
pmc: PMC10087725
doi:
Substances chimiques
Minerals
0
Calcium
SY7Q814VUP
Parathyroid Hormone
0
Types de publication
Review
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2602-2614Informations de copyright
© 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).
Références
Clin Endocrinol (Oxf). 1980 Apr;12(4):385-90
pubmed: 7379319
J Bone Miner Res. 2013 Nov;28(11):2277-85
pubmed: 23661265
Clin Otolaryngol. 2007 Feb;32(1):32-7
pubmed: 17298308
Surgery. 2020 Jan;167(1):124-128
pubmed: 31570150
J Clin Endocrinol Metab. 1995 Jul;80(7):2135-8
pubmed: 7608266
Medicine (Baltimore). 2017 Oct;96(43):e8245
pubmed: 29068988
JAMA. 2019 Dec 24;322(24):2441-2443
pubmed: 31860036
J Bone Miner Res. 2018 May;33(5):822-831
pubmed: 29281760
J Clin Endocrinol Metab. 2021 Apr 23;106(5):e2215-e2227
pubmed: 33484559
J Bone Miner Res. 2008 Dec;23(12):2018-24
pubmed: 18684087
J Clin Endocrinol Metab. 2012 Dec;97(12):4507-14
pubmed: 23043192
Calcif Tissue Int. 2018 Aug;103(2):151-163
pubmed: 29511787
Ann Ital Chir. 2019;90:21-30
pubmed: 30862769
Clin Endocrinol (Oxf). 2015 Jun;82(6):816-23
pubmed: 25640980
Arch Intern Med. 1968 Nov;122(5):408-11
pubmed: 5687928
Endocrinol Metab (Seoul). 2017 Mar;32(1):68-76
pubmed: 28181426
Endocrine. 2019 Nov;66(2):405-415
pubmed: 31317524
Chirurgia (Bucur). 2019 Sept-Oct;114(5):602-610
pubmed: 31670636
J Med Econ. 2019 Nov;22(11):1141-1152
pubmed: 31124721
J Bone Miner Res. 2018 Mar;33(3):478-485
pubmed: 29087618
J Bone Miner Res. 2015 Sep;30(9):1738-44
pubmed: 25753591
Osteoporos Int. 2021 Nov;32(11):2145-2153
pubmed: 34021765
Isr J Med Sci. 1981 Jan;17(1):53-4
pubmed: 7461948
PLoS One. 2020 May 8;15(5):e0232842
pubmed: 32384131
Neurology. 1982 Jul;32(7):779-82
pubmed: 7201117
Clin Endocrinol (Oxf). 2017 Nov;87(5):605-608
pubmed: 28617975
Endocr Pract. 2014 Jul;20(7):671-9
pubmed: 24449664
Eur J Endocrinol. 2004 Jan;150(1):9-18
pubmed: 14713274
Clin Endocrinol (Oxf). 2019 Feb;90(2):285-292
pubmed: 30375660
J Clin Psychiatry. 1988 Aug;49(8):317-8
pubmed: 3045102
J Surg Res. 2015 Aug;197(2):348-53
pubmed: 25982044
J Clin Endocrinol Metab. 2017 Jan 1;102(1):251-258
pubmed: 27813708
Q J Med. 1989 Jan;70(261):53-60
pubmed: 2594948
J Bone Miner Res. 2014 Nov;29(11):2504-10
pubmed: 24806578
Calcif Tissue Int. 2018 Aug;103(2):144-150
pubmed: 29516129
Adv Ther. 2021 Apr;38(4):1876-1888
pubmed: 33687651
Eur J Endocrinol. 2002 Feb;146(2):215-22
pubmed: 11834431
Endocr Connect. 2020 Oct;9(10):955-962
pubmed: 33032262
J Clin Endocrinol Metab. 1999 Feb;84(2):718-22
pubmed: 10022443
Endocrine. 2019 Apr;64(1):176-183
pubmed: 30788669
World J Surg. 2020 Aug;44(8):2692-2698
pubmed: 32322939
Eur J Endocrinol. 2019 Jan 1;180(1):71-78
pubmed: 30407920
J Am Geriatr Soc. 1990 Aug;38(8):884-8
pubmed: 2387952
Langenbecks Arch Surg. 2015 Apr;400(3):319-24
pubmed: 25749741
Am J Emerg Med. 2014 Aug;32(8):945.e1-4
pubmed: 24742362
Nat Rev Dis Primers. 2017 Aug 31;3:17055
pubmed: 28857066
Endocrine. 2014 Nov;47(2):537-42
pubmed: 24563161
Arch Endocrinol Metab. 2016 Nov-Dec;60(6):532-536
pubmed: 27901178
J Clin Endocrinol Metab. 1993 Jun;76(6):1617-21
pubmed: 8501170
Indian J Psychiatry. 2020 Mar-Apr;62(2):217-218
pubmed: 32382186
J Clin Endocrinol Metab. 2020 Apr 1;105(4):
pubmed: 31901096
Clin Endocrinol (Oxf). 2018 Jun;88(6):838-847
pubmed: 29520810
J Bone Miner Res. 2013 Dec;28(12):2570-6
pubmed: 23737456
J Clin Endocrinol Metab. 2016 Jun;101(6):2313-24
pubmed: 26938200
J Int Med Res. 2020 Jun;48(6):300060520927199
pubmed: 32527180
J Clin Endocrinol Metab. 2017 Jan 1;102(1):259-266
pubmed: 27813709
Neurol Sci. 2019 Nov;40(11):2251-2263
pubmed: 31267306
Calcif Tissue Int. 2017 Mar;100(3):278-285
pubmed: 28012105
World J Surg. 1998 Jul;22(7):718-24
pubmed: 9606288
Annu Rev Nutr. 1990;10:233-54
pubmed: 2200464
Head Neck. 2010 Mar;32(3):279-83
pubmed: 19691027
BMC Neurol. 2016 Sep 08;16:165
pubmed: 27608765
Osteoporos Int. 2020 Feb;31(2):327-333
pubmed: 31720712
Arch Endocrinol Metab. 2020 May-Jun;64(3):282-289
pubmed: 32555995
World J Surg. 2013 Jan;37(1):94-101
pubmed: 23052805
Neuroradiology. 1985;27(1):32-7
pubmed: 3974864
J Clin Endocrinol Metab. 2020 Dec 1;105(12):
pubmed: 32918085
J Clin Endocrinol Metab. 2016 Jun;101(6):2273-83
pubmed: 26943719
Braz J Psychiatry. 2016 Oct-Dec;38(4):349-350
pubmed: 27828563
J Clin Endocrinol Metab. 2019 Dec 1;104(12):5795-5803
pubmed: 31305931
Br J Surg. 2018 Sep;105(10):1313-1318
pubmed: 29663312
Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13566-71
pubmed: 15347804
World J Biol Psychiatry. 2007;8(1):56-9
pubmed: 17366354
J Bone Miner Res. 2016 Jul;31(7):1440-8
pubmed: 26865527
J Epidemiol. 2000 Jan;10(1):29-33
pubmed: 10695258
Eur J Endocrinol. 2019 Mar;180(3):P1-P22
pubmed: 30540559
Clin Endocrinol (Oxf). 2019 Apr;90(4):592-600
pubmed: 30589959
J Chem Neuroanat. 2016 Dec;78:20-24
pubmed: 27475519
Clin Endocrinol (Oxf). 2011 Dec;75(6):760-5
pubmed: 21645025
World J Surg. 2014 Oct;38(10):2613-20
pubmed: 24791907
J Clin Endocrinol Metab. 2021 Jun 16;106(7):1900-1917
pubmed: 33788935
Acta Ophthalmol (Copenh). 1962;40:255-65
pubmed: 14487411
Endocr Connect. 2020 Jul;9(7):627-636
pubmed: 32580149
Endocrine. 2021 May;72(2):553-561
pubmed: 33655415
Ann Surg. 2021 Dec 1;274(6):e1202-e1208
pubmed: 32032086
Clin Endocrinol (Oxf). 2012 Aug;77(2):200-6
pubmed: 22288727
Eur J Endocrinol. 2015 Aug;173(2):G1-20
pubmed: 26160136
Horm Metab Res. 2019 Jun;51(6):362-366
pubmed: 31207657
J Clin Endocrinol Metab. 2016 Aug;101(8):3045-53
pubmed: 27186861
Gland Surg. 2020 Apr;9(2):245-251
pubmed: 32420248
BMC Endocr Disord. 2013 Jan 03;13:1
pubmed: 23286605
AMA Arch Ophthalmol. 1953 Oct;50(4):455-61
pubmed: 13091520