Influence of intensive lipid-lowering on CT derived fractional flow reserve in patients with stable chest pain: Rationale and design of the FLOWPROMOTE study.
Angina, Stable
Atorvastatin
Ezetimibe
/ therapeutic use
Fractional Flow Reserve, Myocardial
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/ therapeutic use
Plaque, Atherosclerotic
Predictive Value of Tests
Prospective Studies
Rosuvastatin Calcium
Severity of Illness Index
Tomography, X-Ray Computed
angina
coronary artery disease
fractional flow reserve
imaging
lipid lowering
statins
testing
Journal
Clinical cardiology
ISSN: 1932-8737
Titre abrégé: Clin Cardiol
Pays: United States
ID NLM: 7903272
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
20
07
2022
received:
04
05
2022
accepted:
01
08
2022
pubmed:
4
9
2022
medline:
19
10
2022
entrez:
3
9
2022
Statut:
ppublish
Résumé
Coronary CT angiography (CTA) derived fractional flow reserve (FFR To test whether lipid lowering therapy is associated with significant improvement in FFR Investigator driven, prospective, multicenter, randomized study of patients with stable angina, coronary stenosis ≥50% determined by clinically indicated first-line CTA, and FFR The results of this study will provide novel insights into the interplay between lipid lowering, and the pathophysiology in coronary artery disease.
Identifiants
pubmed: 36056636
doi: 10.1002/clc.23895
pmc: PMC9574753
doi:
Substances chimiques
Hydroxymethylglutaryl-CoA Reductase Inhibitors
0
Rosuvastatin Calcium
83MVU38M7Q
Atorvastatin
A0JWA85V8F
Ezetimibe
EOR26LQQ24
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
986-994Subventions
Organisme : Novo Nordisk Fonden
ID : NNF18OC0052504
Organisme : Novo Nordisk Fonden
ID : NNF21OC0068200
Informations de copyright
© 2022 The Authors. Clinical Cardiology published by Wiley Periodicals, LLC.
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