Congenital midline spinal hamartoma in an infant with DICER1 syndrome: A case report.

DICER1 cancer predisposition case report congenital midline spinal hamartoma infant

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2022
Historique:
received: 07 06 2022
accepted: 29 07 2022
entrez: 5 9 2022
pubmed: 6 9 2022
medline: 6 9 2022
Statut: epublish

Résumé

Congenital spinal hamartomas are rare benign tumors. They are mostly seen in infants and are typically asymptomatic at presentation. Spinal hamartomas have not been associated with any known cancer predisposition syndrome. DICER1 syndrome is a well-characterized cancer predisposition syndrome caused by a germline mutation in the

Identifiants

pubmed: 36059709
doi: 10.3389/fonc.2022.963768
pmc: PMC9433698
doi:

Types de publication

Case Reports

Langues

eng

Pagination

963768

Informations de copyright

Copyright © 2022 Hammad, Lo, Chen, Shroff, Malkin, Villani and Denburg.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

World Neurosurg. 2021 Jan;145:142-147
pubmed: 32949805
Nature. 2004 Nov 11;432(7014):231-5
pubmed: 15531879
F1000Res. 2015 Jul 10;4:214
pubmed: 26925222
Science. 2009 Aug 21;325(5943):965
pubmed: 19556464
Oncogene. 2014 Nov 6;33(45):5295-302
pubmed: 24909177
Rhinol Online. 2020;3:15-24
pubmed: 34164613
J Otolaryngol Head Neck Surg. 2015 Jul 03;44:28
pubmed: 26138824
J Neurosurg Pediatr. 2016 Aug;18(2):177-82
pubmed: 27127875
N Engl J Med. 2019 May 9;380(19):1834-1842
pubmed: 31067372
Mod Pathol. 2015 Dec;28(12):1603-12
pubmed: 26428316
AJNR Am J Neuroradiol. 1989 Sep-Oct;10(5 Suppl):S101
pubmed: 2505546
Hum Genet. 2014 Nov;133(11):1443-50
pubmed: 25118636
J Neurosurg. 1998 Jun;88(6):954-7
pubmed: 9609287
Childs Nerv Syst. 2006 Sep;22(9):1098-102
pubmed: 16328392
AJNR Am J Neuroradiol. 2006 Apr;27(4):810-2
pubmed: 16611769
J Pediatr. 1976 Dec;89(6):928-933
pubmed: 792410
J Pediatr. 1996 Feb;128(2):220-4
pubmed: 8636815
Clin Cancer Res. 2018 May 15;24(10):2251-2261
pubmed: 29343557
AJNR Am J Neuroradiol. 1999 Jun-Jul;20(6):1169-71
pubmed: 10445466
Acta Neuropathol. 2020 Apr;139(4):689-701
pubmed: 30953130
J Clin Oncol. 2019 Mar 10;37(8):668-676
pubmed: 30715996

Auteurs

Rawan Hammad (R)

Division of Pediatric Hematology and Oncology, The Hospital for Sick Children, Toronto, ON, Canada.
Division of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Winnie Lo (W)

Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.

Haiying Chen (H)

Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.

Manohar Shroff (M)

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada.

David Malkin (D)

Division of Pediatric Hematology and Oncology, The Hospital for Sick Children, Toronto, ON, Canada.

Anita Villani (A)

Division of Pediatric Hematology and Oncology, The Hospital for Sick Children, Toronto, ON, Canada.

Avram Denburg (A)

Division of Pediatric Hematology and Oncology, The Hospital for Sick Children, Toronto, ON, Canada.

Classifications MeSH