Alkaline-sensitive two-pore domain potassium channels form functional heteromers in pancreatic β-cells.

Humans Potassium Channels, Tandem Pore Domain / genetics Insulin-Secreting Cells / metabolism Hydrogen-Ion Concentration Insulin / metabolism Alkalosis Potassium / metabolism
electrophysiology ion channel oligomerization pH regulation pancreas transcriptomics

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
10 2022
Historique:
received: 08 11 2021
revised: 26 08 2022
accepted: 29 08 2022
pubmed: 6 9 2022
medline: 3 11 2022
entrez: 5 9 2022
Statut: ppublish

Résumé

Two-pore domain K

Identifiants

DOI: 10.1016/j.jbc.2022.102447 PMID: 36063992 PMC: PMC9520024
pubmed: 36063992
pii: S0021-9258(22)00890-0
doi: 10.1016/j.jbc.2022.102447
pmc: PMC9520024
pii:
doi:

Substances chimiques

Potassium Channels, Tandem Pore Domain 0
Insulin 0
Potassium RWP5GA015D

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102447

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article.

Auteurs

Lamyaa Khoubza (L)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France.

Nicolas Gilbert (N)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France.

Eun-Jin Kim (EJ)

Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju, South Korea.

Franck C Chatelain (FC)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France.

Sylvain Feliciangeli (S)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France; Inserm, Paris, France.

Sophie Abelanet (S)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France.

Dawon Kang (D)

Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju, South Korea.

Florian Lesage (F)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France; Inserm, Paris, France. Electronic address: lesage@ipmc.cnrs.fr.

Delphine Bichet (D)

Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, Valbonne, France.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Alkaline-sensitive two-pore domain potassium...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques à pores à domaines en tandem › Alkaline-sensitive two-pore domain potassium...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules entéroendocrines › Cellules à insuline › Alkaline-sensitive two-pore domain potassium...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › Alkaline-sensitive two-pore domain potassium...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Alkaline-sensitive two-pore domain potassium...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'équilibre acidobasique › Alcalose › Alkaline-sensitive two-pore domain potassium...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Potassium › Alkaline-sensitive two-pore domain potassium...