Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury.
Acute kidney injury
Clinical trials
Intensive care unit
Renal replacement therapy
Journal
Intensive care medicine
ISSN: 1432-1238
Titre abrégé: Intensive Care Med
Pays: United States
ID NLM: 7704851
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
received:
04
05
2022
accepted:
29
07
2022
pubmed:
7
9
2022
medline:
15
9
2022
entrez:
6
9
2022
Statut:
ppublish
Résumé
Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume excess until kidney function recovers. This review is intended to provide a comprehensive update on key aspects of RRT prescription and delivery to critically ill patients. Recently completed trials have enhanced the evidence base regarding several RRT practices, most notably the timing of RRT initiation and anticoagulation for continuous therapies. Better evidence is still needed to clarify several aspects of care including optimal targets for ultrafiltration and effective strategies for RRT weaning and discontinuation.
Identifiants
pubmed: 36066597
doi: 10.1007/s00134-022-06851-6
pii: 10.1007/s00134-022-06851-6
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1368-1381Informations de copyright
© 2022. Springer-Verlag GmbH Germany, part of Springer Nature.
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