Pars-plana-vitrectomy for endophthalmitis treatment and the role of standardized ultrasound.


Journal

International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294

Informations de publication

Date de publication:
Apr 2023
Historique:
received: 11 05 2022
accepted: 28 08 2022
medline: 20 4 2023
pubmed: 7 9 2022
entrez: 6 9 2022
Statut: ppublish

Résumé

Endophthalmitis is a severe inflammation following surgery or endogenous spread of pathogens. Besides clinical signs and symptoms, standardized ultrasound might help to confirm the diagnosis. Thus, we analyzed 172 cases of endophthalmitis for pathogens, visual acuity (VA) and the predictive value of standardized ultrasound. Retrospective analysis of patients treated with pars-plana-vitrectomy for endophthalmitis at the University Eye Hospital was performed. Sex, age, VA at presentation, first day after surgery, four weeks postoperatively, and at last follow-up, as well as pathogen culture, and presence of standardized ultrasound before vitrectomy were recorded. Mann-Whitney U and Chi-square tests were used for groupwise comparisons. A total of 172 patients (male = 47.7%) with a median age of 76 years (IQR 65-82 years) treated for endophthalmitis (exogenous = 85.5%) were included. Median follow-up time was 65 days (IQR 12-274 days). Visual acuity at presentation was 2.30 logMAR (IQR 2.70-2.30 logMAR); it increased to 1.00 logMAR (1.4-0.40 logMAR) at last follow-up. A total of 79 patients (45.9%) underwent standardized ultrasound before vitrectomy. Patients with positive ultrasound criteria had a significantly decreased VA at presentation (p = 0.034). Positive microbiological cultures for Streptococcus spp. and Enterococcus faecalis were associated with decreased VA (p = 0.028) at last follow-up. Standardized ultrasound is an easy and robust tool in the diagnosis of endophthalmitis. Positive criteria are significantly associated with decreased VA at presentation. The recovery of VA depends on pathogens and is significantly worse for certain species (Streptococcus spp., Enterococcus faecalis).

Identifiants

pubmed: 36066783
doi: 10.1007/s10792-022-02508-x
pii: 10.1007/s10792-022-02508-x
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1111-1119

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature B.V.

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Auteurs

Valerie Schmelter (V)

Department of Ophthalmology, Ludwig-Maximilians Universität, Mathildenstr. 8, 80336, Munich, Germany. valerie.schmelter@med.uni-muenchen.de.

Frederick Schneider (F)

Department of Anaesthesiology, Technical University of Munich, TUM School of Medicine, Munich, Germany.

Siegfried G Priglinger (SG)

Department of Ophthalmology, Ludwig-Maximilians Universität, Mathildenstr. 8, 80336, Munich, Germany.

Raffael Liegl (R)

University Eye Hospital, University of Bonn, Bonn, Germany.

Thomas C Kreutzer (TC)

Department of Ophthalmology, Ludwig-Maximilians Universität, Mathildenstr. 8, 80336, Munich, Germany.

Paul Foerster (P)

Department of Ophthalmology, Ludwig-Maximilians Universität, Mathildenstr. 8, 80336, Munich, Germany.

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