Feasibility of oncology clinical trial-embedded evaluation of social determinants of health.
health equity
research methods
social determinants of health
Journal
Pediatric blood & cancer
ISSN: 1545-5017
Titre abrégé: Pediatr Blood Cancer
Pays: United States
ID NLM: 101186624
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
revised:
25
07
2022
received:
11
04
2022
accepted:
29
07
2022
pubmed:
8
9
2022
medline:
1
10
2022
entrez:
7
9
2022
Statut:
ppublish
Résumé
Social determinants of health (SDoH) are associated with stark disparities in cancer outcomes, but systematic SDoH data collection is virtually absent from oncology clinical trials. Trial-based SDoH data are essential to ensure representation of marginalized populations, contextualize outcome disparities, and identify health-equity intervention opportunities. We report the feasibility of a pediatric oncology multicenter therapeutic trial-embedded SDoH investigation. Among 448 trial participants, 392 (87.5%) opted-in to the embedded SDoH study; 375 (95.7%) completed baseline surveys, with high longitudinal response rates (88.9-93.1%) over 24 months. Trial-embedded SDoH data collection is feasible and acceptable and must be consistently included within future oncology trials.
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e29933Subventions
Organisme : NCI NIH HHS
ID : K07 CA211847
Pays : United States
Informations de copyright
© 2022 Wiley Periodicals LLC.
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