Vaccination willingness in association with personality traits in patients with multiple sclerosis in the course of SARS-CoV-2 pandemic.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
07 09 2022
Historique:
received: 22 12 2021
accepted: 22 08 2022
entrez: 7 9 2022
pubmed: 8 9 2022
medline: 11 9 2022
Statut: epublish

Résumé

Vaccination is a key strategy for controlling the SARS-CoV-2 pandemic. Acceptance of SARS-CoV-2 vaccines by chronically ill patients, such as multiple sclerosis (MS) patients, plays an important role in prevention of complicated disease course. This longitudinal, prospective, multi-centre-study of German MS-patients aimed to detect socio-demographic, clinical, or psychological determinants of attitudes towards standard vaccines, SARS-CoV-2 vaccines, and governmental measures before/during the pandemic. Exactly 404 MS-patients were investigated by standardized questionnaires and structured interviews on socio-demographic, clinical-neurological, and psychological characteristics, vaccination status, and vaccination from June 2019. Data on SARS-CoV-2 vaccination willingness were collected in two follow-up assessments (1st: June to July 2020, before SARS-CoV-2 vaccine availability, N = 200; 2nd: March to May 2021, after SARS-CoV-2 vaccine availability, N = 157). Age, sex, MS course type, depression, and personality characteristics (Extraversion, Novelty seeking, Self-directedness, and Cooperativeness) were significantly associated with vaccination willingness. Although the majority of MS-patients showed SARS-CoV-2 vaccination willingness at both follow-ups (1st: 60%, 2nd: 61%), a substantial proportion had concerns and were undecided or opposed to vaccination. Socio-demographic variables like age and sex, psychopathological status, and various personality characteristics might influence vaccination willingness and should be considered when discussing with MS-patients about SARS-CoV-2 vaccination.

Identifiants

pubmed: 36071083
doi: 10.1038/s41598-022-18912-3
pii: 10.1038/s41598-022-18912-3
pmc: PMC9449937
doi:

Substances chimiques

Antibodies, Viral 0
COVID-19 Vaccines 0
Viral Vaccines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

15147

Informations de copyright

© 2022. The Author(s).

Références

Lancet Infect Dis. 2022 Feb;22(2):183-195
pubmed: 34756186
Lancet. 2018 Apr 21;391(10130):1622-1636
pubmed: 29576504
Lancet Neurol. 2018 Feb;17(2):162-173
pubmed: 29275977
Clin Infect Dis. 2020 Jul 28;71(15):703-705
pubmed: 32282038
Front Psychol. 2020 Oct 19;11:575950
pubmed: 33192883
Arch Gen Psychiatry. 1993 Dec;50(12):975-90
pubmed: 8250684
J Med Life. 2021 Mar-Apr;14(2):225-237
pubmed: 34104246
Autoimmun Rev. 2017 Sep;16(9):925-936
pubmed: 28698092
J Neurol Neurosurg Psychiatry. 2021 Oct;92(10):1033-1043
pubmed: 34353858
Front Mol Biosci. 2021 Mar 25;8:635245
pubmed: 33869282
Int J Soc Psychiatry. 2020 Aug;66(5):504-511
pubmed: 32380879
BMJ. 2021 Sep 15;374:n2211
pubmed: 34526310
Vaccine. 2020 Nov 17;38(49):7789-7798
pubmed: 33109389
Science. 2021 Jul 9;373(6551):147
pubmed: 34244391
Nat Rev Dis Primers. 2018 Nov 8;4(1):43
pubmed: 30410033
BMJ. 2021 Mar 11;372:n699
pubmed: 33707182
Science. 2021 Jul 30;373(6554):479
pubmed: 34326217
Age Ageing. 2021 Feb 26;50(2):279-283
pubmed: 33320183
Ann Intern Med. 2020 Dec 15;173(12):964-973
pubmed: 32886525
Arq Neuropsiquiatr. 2015 Mar;73(3):200-4
pubmed: 25807124
J Intern Med. 2015 Oct;278(4):369-95
pubmed: 26212387
Mult Scler. 2019 Oct;25(12):1641-1652
pubmed: 30230952
Eur Neurol. 2022;85(2):104-111
pubmed: 34743082
Vaccine. 2020 Sep 29;38(42):6500-6507
pubmed: 32863069
Assessment. 2011 Mar;18(1):39-49
pubmed: 20484711
Curr Opin Neurol. 2020 Jun;33(3):286-294
pubmed: 32374570
Isr J Health Policy Res. 2021 Mar 19;10(1):26
pubmed: 33741063
Int Immunopharmacol. 2021 Aug;97:107724
pubmed: 33951558
Mult Scler Relat Disord. 2020 Jun;41:102164
pubmed: 32388452
Mult Scler Relat Disord. 2020 Nov;46:102512
pubmed: 32977074
Neurology. 1983 Nov;33(11):1444-52
pubmed: 6685237
Nat Rev Neurol. 2022 May;18(5):289-306
pubmed: 35388213
Lancet Psychiatry. 2020 Jun;7(6):547-560
pubmed: 32304649
J Gen Intern Med. 2020 Aug;35(8):2296-2303
pubmed: 32472486
Mult Scler Relat Disord. 2021 Jun;51:102880
pubmed: 33740481
J Neurol. 2021 May;268(5):1598-1607
pubmed: 32813051
Front Psychol. 2020 Jun 18;11:1491
pubmed: 32625157
Cardiovasc Pathol. 2021 Jan - Feb;50:107278
pubmed: 32889088
Mult Scler Relat Disord. 2021 Apr;49:102788
pubmed: 33508570
JAMA Netw Open. 2020 Oct 1;3(10):e2025594
pubmed: 33079199
PLoS One. 2021 May 10;16(5):e0248372
pubmed: 33970933
Front Immunol. 2019 Aug 07;10:1883
pubmed: 31440255
Acta Psychiatr Scand. 2003 Mar;107(3):216-21
pubmed: 12580829
EBioMedicine. 2020 Jun;56:102822
pubmed: 32535547
Int J Environ Res Public Health. 2021 Jul 22;18(15):
pubmed: 34360063
Eur J Health Econ. 2020 Sep;21(7):977-982
pubmed: 32591957
Mult Scler J Exp Transl Clin. 2021 May 31;7(2):20552173211017159
pubmed: 34104472
Br J Psychiatry. 2002 Aug;181:158-62
pubmed: 12151288
Nat Rev Neurol. 2016 Apr;12(4):217-33
pubmed: 26943779
Autoimmun Rev. 2016 Mar;15(3):210-20
pubmed: 26589194
N Engl J Med. 2018 Jan 11;378(2):169-180
pubmed: 29320652
BMJ. 2021 Nov 2;375:n2635
pubmed: 34728500

Auteurs

Felicita Heidler (F)

Department of Neurology, Ecumenic Hainich Hospital gGmbH, Pfafferode 102, 99974, Mühlhausen, Germany.

Julia Baldt (J)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.

Niklas Frahm (N)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany. niklas-frahm@gmx.de.

Silvan Elias Langhorst (SE)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.

Pegah Mashhadiakbar (P)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.

Barbara Streckenbach (B)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.

Katja Burian (K)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.

Uwe Klaus Zettl (UK)

Department of Neurology, Neuroimmunology Section, University Medical Centre of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.

Jörg Richter (J)

Department of Neurology, Ecumenic Hainich Hospital gGmbH, Pfafferode 102, 99974, Mühlhausen, Germany.
Faculty of Health Sciences, University of Hull, Hull, UK.
Durham Law School, Durham University, Durham, UK.

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