Iatrogenic and spontaneous preterm birth in England: A population-based cohort study.
iatrogenic
induction
preterm birth
spontaneous
Journal
BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
revised:
10
08
2022
received:
10
01
2022
accepted:
22
08
2022
pubmed:
9
9
2022
medline:
7
12
2022
entrez:
8
9
2022
Statut:
ppublish
Résumé
To describe the rates of and risk factors associated with iatrogenic and spontaneous preterm birth and the variation in rates between hospitals. Cohort study using electronic health records. English National Health Service. Singleton births between 1 April 2015 and 31 March 2017. Multivariable Poisson regression models were used to estimate adjusted risk ratios (adjRR) to measure association with maternal demographic and clinical risk factors. Preterm births (<37 weeks of gestation) were defined as iatrogenic or spontaneous according to mode of onset of labour. Of the births, 6.1% were preterm and of these, 52.8% were iatrogenic. The proportion of preterm births that were iatrogenic increased after 32 weeks. Both sub-groups were associated with previous preterm birth, extremes of maternal age, socio-economic deprivation and smoking. Iatrogenic preterm birth was associated with higher body mass index (BMI) (BMI >40 kg/m Just over half of all preterm births resulted from iatrogenic intervention. Iatrogenic births have overlapping but different patterns of maternal demographic and clinical risk factors to spontaneous preterm births. Iatrogenic and spontaneous sub-groups should therefore be measured and monitored separately, as well as in aggregate, to facilitate different prevention strategies. This is feasible using routinely acquired hospital data.
Identifiants
pubmed: 36073305
doi: 10.1111/1471-0528.17291
pmc: PMC10092353
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
33-41Subventions
Organisme : Scottish and Welsh Governments
Organisme : NHS England
Organisme : Healthcare Quality Improvement Partnership (HQIP)
Investigateurs
Andrea Blotkamp
(A)
Fran Carroll
(F)
Megan Coe
(M)
George Dunn
(G)
Rebecca Geary
(R)
Alissa Harvey
(A)
Emma Heighway
(E)
Asma Khalil
(A)
Julia Langham
(J)
Lindsey Mamza
(L)
Patrick Muller
(P)
Natalie Moitt
(N)
Sophie Relph
(S)
Louise Thomas
(L)
Lara Waite
(L)
Kirstin Webster
(K)
Informations de copyright
© 2022 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.
Références
JAMA Netw Open. 2019 Apr 5;2(4):e192514
pubmed: 31002320
Lancet. 2013 Jan 19;381(9862):184-5
pubmed: 23158880
Am J Public Health. 2019 Nov;109(11):1597-1604
pubmed: 31536409
BJOG. 2015 Oct;122(11):1495-505
pubmed: 26219352
Acta Obstet Gynecol Scand. 2021 Jul;100(7):1230-1238
pubmed: 33382080
Am J Public Health. 2007 Jan;97(1):157-62
pubmed: 17138924
BJOG. 2014 Mar;121(4):417-21
pubmed: 24314110
BJOG. 2023 Jan;130(1):33-41
pubmed: 36073305
BJOG. 2015 Oct;122(11):1525-34
pubmed: 25626593
J Perinat Med. 2016 Jul 1;44(5):505-9
pubmed: 26646020
Eur J Obstet Gynecol Reprod Biol. 2020 Apr;247:111-115
pubmed: 32087421
Lancet. 2019 Sep 28;394(10204):1181-1190
pubmed: 31472930
Lancet Glob Health. 2016 Feb;4(2):e98-e108
pubmed: 26795602
BJOG. 2014 Mar;121 Suppl 1:101-9
pubmed: 24641540
Stat Med. 2011 Feb 20;30(4):377-99
pubmed: 21225900
Arch Dis Child. 2019 May;104(5):456-465
pubmed: 30413489
Paediatr Respir Rev. 2017 Mar;22:3-10
pubmed: 26482273
BJOG. 2013 Oct;120(11):1356-65
pubmed: 23700966
BMC Pregnancy Childbirth. 2011 May 25;11:39
pubmed: 21612655
Birth. 2020 Mar;47(1):105-114
pubmed: 31746027
J Clin Epidemiol. 2014 May;67(5):578-85
pubmed: 24411310
Pediatrics. 2009 Feb;123(2):e312-27
pubmed: 19171583
Lancet. 2008 Jan 5;371(9606):75-84
pubmed: 18177778
BJOG. 2014 Jan;121(2):183-92
pubmed: 24251861
N Engl J Med. 2008 Jul 17;359(3):262-73
pubmed: 18635431
Stat Med. 2005 Apr 30;24(8):1185-202
pubmed: 15568194