IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation.
IL-17A
fibrosis
human liver
human liver slice culture
type 3 inflammation
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
29 Aug 2022
29 Aug 2022
Historique:
received:
16
07
2022
revised:
23
08
2022
accepted:
25
08
2022
entrez:
9
9
2022
pubmed:
10
9
2022
medline:
14
9
2022
Statut:
epublish
Résumé
IL-17A is considered to guide liver inflammation and fibrosis. From twenty-two human liver samples of different fibrosis stages (F0 to F4), IL-17A, IL-22, and TGFβ1 protein expression in liver tissue lysates were analyzed. Ten paired samples of liver tissue (F0-F1 stage) and blood from the same patient were used to analyze intrahepatic and blood T-lymphoid IL-17A
Identifiants
pubmed: 36077175
pii: ijms23179773
doi: 10.3390/ijms23179773
pmc: PMC9456490
pii:
doi:
Substances chimiques
IL17A protein, human
0
Interleukin-17
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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