The Molecular Predictive and Prognostic Biomarkers in Metastatic Breast Cancer: The Contribution of Molecular Profiling.

biomarker metastatic breast cancer molecular biology molecular profilig precision medicine targeted therapy

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
30 Aug 2022
Historique:
received: 01 07 2022
revised: 16 08 2022
accepted: 20 08 2022
entrez: 9 9 2022
pubmed: 10 9 2022
medline: 10 9 2022
Statut: epublish

Résumé

The past decade was marked by several important studies deciphering the molecular landscape of metastatic breast cancer. Although the initial goal of these studies was to find driver oncogenic events to explain cancer progression and metastatic spreading, they have also permitted the identification of several molecular alterations associated with treatment response or resistance. Herein, we review validated (

Identifiants

pubmed: 36077738
pii: cancers14174203
doi: 10.3390/cancers14174203
pmc: PMC9454488
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Références

Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10393-8
pubmed: 12917485
Sci Adv. 2016 Oct 07;2(10):e1601737
pubmed: 27730215
Ann Oncol. 2018 Sep 1;29(9):1895-1902
pubmed: 30137196
ESMO Open. 2016 Mar 18;1(2):e000023
pubmed: 27843590
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74
pubmed: 11553815
Nature. 2013 Aug 22;500(7463):415-21
pubmed: 23945592
Nat Commun. 2017 Jun 06;8:15180
pubmed: 28585546
N Engl J Med. 2021 Apr 22;384(16):1529-1541
pubmed: 33882206
Ann Oncol. 2018 Mar 1;29(3):640-645
pubmed: 29236940
J Clin Oncol. 2016 Jun 20;34(18):2115-24
pubmed: 27091708
J Surg Oncol. 2002 Apr;79(4):216-23
pubmed: 11920778
Breast Cancer Res Treat. 2011 Jun;127(2):407-16
pubmed: 20617378
Ann Oncol. 2020 Mar;31(3):377-386
pubmed: 32067679
N Engl J Med. 2018 Nov 29;379(22):2108-2121
pubmed: 30345906
Cancer Cell. 2018 Sep 10;34(3):427-438.e6
pubmed: 30205045
N Engl J Med. 2019 May 16;380(20):1929-1940
pubmed: 31091374
N Engl J Med. 1998 Nov 26;339(22):1609-18
pubmed: 9828250
Ann Oncol. 2015 Jan;26(1):120-125
pubmed: 25361980
Cancer Res. 2017 Sep 1;77(17):4567-4578
pubmed: 28698210
ESMO Open. 2022 Feb;7(1):100336
pubmed: 34953399
Lancet. 2020 Dec 5;396(10265):1817-1828
pubmed: 33278935
ESMO Open. 2021 Oct;6(5):100230
pubmed: 34479035
J Clin Oncol. 2016 Feb 10;34(5):419-26
pubmed: 26503204
JCO Precis Oncol. 2017;2017:
pubmed: 29623306
Nature. 2019 May;569(7757):560-564
pubmed: 31118521
Eur Urol. 2016 May;69(5):855-62
pubmed: 26343003
J Clin Oncol. 2016 Sep 1;34(25):2961-8
pubmed: 27269946
N Engl J Med. 2019 Jul 25;381(4):307-316
pubmed: 31166679
Nature. 2012 Oct 4;490(7418):61-70
pubmed: 23000897
Cancer Res. 2017 Sep 1;77(17):4579-4588
pubmed: 28655787
Ann Oncol. 2020 Nov;31(11):1491-1505
pubmed: 32853681
Cancer Discov. 2018 Nov;8(11):1390-1403
pubmed: 30206110
N Engl J Med. 2022 Mar 24;386(12):1143-1154
pubmed: 35320644
Ann Oncol. 2019 Mar 1;30(3):397-404
pubmed: 30475950
JNCI Cancer Spectr. 2018 Dec 13;2(4):pky056
pubmed: 31360876
Ann Oncol. 2019 Mar 1;30(3):365-373
pubmed: 30715161
Cancer Cell. 2002 Nov;2(5):367-76
pubmed: 12450792
Eur J Cancer. 1992;28(1):34-7
pubmed: 1567686
Nature. 2014 Mar 20;507(7492):315-22
pubmed: 24476821
J Clin Oncol. 2004 Jun 15;22(12):2284-93
pubmed: 15136595
J Clin Oncol. 2002 Feb 1;20(3):719-26
pubmed: 11821453
Nat Genet. 2019 Oct;51(10):1450-1458
pubmed: 31570896
Cancer Discov. 2021 Nov;11(11):2796-2811
pubmed: 34183353
JCO Precis Oncol. 2019 Dec 5;3:
pubmed: 32923864
J Clin Oncol. 2020 Dec 20;38(36):4274-4282
pubmed: 33119476
Br J Cancer. 2017 Jun 27;117(1):113-123
pubmed: 28535155
Ann Oncol. 2019 Jan 1;30(1):115-123
pubmed: 30423024
JAMA Oncol. 2018 Oct 1;4(10):1335-1343
pubmed: 29902286
Nat Med. 2021 Feb;27(2):250-255
pubmed: 33462450
N Engl J Med. 2022 Jul 7;387(1):9-20
pubmed: 35665782
N Engl J Med. 2016 Nov 17;375(20):1925-1936
pubmed: 27959613
Nat Genet. 2013 Oct;45(10):1113-20
pubmed: 24071849
Br J Cancer. 1957 Sep;11(3):359-77
pubmed: 13499785
Nature. 2012 Sep 27;489(7417):519-25
pubmed: 22960745
Ann Oncol. 2019 Apr 1;30(4):558-566
pubmed: 30689707
J Clin Oncol. 2021 Aug 1;39(22):2443-2451
pubmed: 33844595
J Clin Oncol. 2020 Feb 10;38(5):423-433
pubmed: 31841354
NPJ Breast Cancer. 2019 Jan 17;5:5
pubmed: 30675515
Breast Cancer Res Treat. 2022 Feb;191(3):565-576
pubmed: 34860318
Nat Genet. 2019 Feb;51(2):202-206
pubmed: 30643254
JCO Precis Oncol. 2022 Mar;6:e2100370
pubmed: 35357905
N Engl J Med. 2018 Aug 23;379(8):753-763
pubmed: 30110579
Nat Rev Genet. 2006 Aug;7(8):606-19
pubmed: 16847462
Cell. 2015 Oct 8;163(2):506-19
pubmed: 26451490
Ann Oncol. 2016 Aug;27(8):1532-8
pubmed: 27194814
Oncologist. 2020 Jul;25(7):e1109-e1116
pubmed: 32272491
Nat Genet. 2019 Feb;51(2):207-216
pubmed: 30531871
Ann Oncol. 2008 Feb;19(2):315-20
pubmed: 17804473
Lancet Oncol. 2017 Oct;18(10):1360-1372
pubmed: 28800861
Nat Med. 2017 Apr;23(4):517-525
pubmed: 28288110

Auteurs

Benjamin Verret (B)

Medical Oncology Department, Gustave Roussy Cancer Campus, 94800 Villejuif, France.
INSERM Unit U981, Gustave Roussy Cancer Campus, 94805 Villejuif, France.

Michele Bottosso (M)

INSERM Unit U981, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Department of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.

Sofia Hervais (S)

INSERM Unit U981, Gustave Roussy Cancer Campus, 94805 Villejuif, France.

Barbara Pistilli (B)

Medical Oncology Department, Gustave Roussy Cancer Campus, 94800 Villejuif, France.

Classifications MeSH