Vitamin D Supplementation and COVID-19 Outcomes: Mounting Evidence and Fewer Doubts.
COVID-19
Cholecalciferol
SARS-CoV-2
immune function
mortality
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
31 Aug 2022
31 Aug 2022
Historique:
received:
13
08
2022
accepted:
25
08
2022
entrez:
9
9
2022
pubmed:
10
9
2022
medline:
14
9
2022
Statut:
epublish
Résumé
The coronavirus disease 2019 (COVID-19) has already killed more than 6 million people around the world. A growing body of epidemiological evidence suggests that low 25-hydroxy vitamin D (25-OH-vitamin D) plasma levels are associated with an increased risk of developing COVID-19 and -most importantly-with a higher risk of developing more severe COVID-19 and dying. On the other hand, vitamin D supplementation during the early phases of COVID-19 has been related to a decreased length of hospital stay, less frequent need for oxygen, and a reduced mortality rate in inpatients. This seems to be particularly true when high dosages are used. In light of this evidence, further studies are needed to define the best timing for vitamin D supplementation and the most effective dosage schedule.
Identifiants
pubmed: 36079842
pii: nu14173584
doi: 10.3390/nu14173584
pmc: PMC9460517
pii:
doi:
Substances chimiques
Vitamins
0
Vitamin D
1406-16-2
Types de publication
Editorial
Langues
eng
Sous-ensembles de citation
IM
Références
J Pharm Pharm Sci. 2022;25:84-92
pubmed: 35245430
Front Pharmacol. 2022 Jul 04;13:863587
pubmed: 35860019
Clin Nutr ESPEN. 2022 Aug;50:322-325
pubmed: 35871942
Nutrients. 2022 Apr 14;14(8):
pubmed: 35458203
PLoS One. 2022 Jul 6;17(7):e0268396
pubmed: 35793346
Complement Ther Med. 2022 Nov;70:102855
pubmed: 35868492
N Engl J Med. 2022 Jul 28;387(4):299-309
pubmed: 35939577
Dev Change. 2022 May 05;:
pubmed: 35942175
Nutrients. 2022 Jun 29;14(13):
pubmed: 35807895
Nutrients. 2021 Jan 22;13(2):
pubmed: 33499027
Front Nutr. 2022 Jul 05;9:934258
pubmed: 35866079
BMJ Open. 2022 Aug 4;12(8):e059477
pubmed: 35926985
Nutrients. 2022 Jul 26;14(15):
pubmed: 35893907
BMC Med. 2022 Feb 18;20(1):83
pubmed: 35177066
Eur J Transl Myol. 2022 Apr 20;32(2):
pubmed: 35441835
Aging Dis. 2022 Jul 11;13(4):960-969
pubmed: 35855327
PLoS Med. 2022 May 31;19(5):e1003999
pubmed: 35639792
Adv Respir Med. 2021;89(2):145-157
pubmed: 33966262
Sci Rep. 2022 Jul 11;12(1):11741
pubmed: 35817805
Nutrients. 2020 Dec 11;12(12):
pubmed: 33322317
BMJ. 2017 Feb 15;356:i6583
pubmed: 28202713
Nutrients. 2021 Dec 28;14(1):
pubmed: 35010990
Nutrients. 2022 Apr 13;14(8):
pubmed: 35458189