Optimization of Flavonoid Extraction from
Willow Buds
antibacterial
antioxidation
chemical component
extraction technology
total flavonoids
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
03 Sep 2022
03 Sep 2022
Historique:
received:
27
07
2022
revised:
31
08
2022
accepted:
01
09
2022
entrez:
9
9
2022
pubmed:
10
9
2022
medline:
14
9
2022
Statut:
epublish
Résumé
The present study was designed to evaluate the chemical extraction, chemical composition, and antioxidant and antibacterial properties of the total flavonoids in Willow Buds (TFW). We investigated the optimal extraction of TFW using response surface methodology (RSM). Chemical compounds were analyzed using Q-Orbitrap LC-MS/MS. The DPPH radical scavenging capacity, hydroxy radical inhibitory ability, and superoxide anion radical inhibitory ability were explored to determine the antioxidant properties of flavonoid extractions. The antibacterial effect was assessed via minimal inhibitory concentration. The results demonstrated that the optimal extraction conditions were an ethanol concentration of 50%, a time of 35 min, and a liquid/material ratio of 70:1 mL/g. Under these conditions, the yield of TFW was 7.57%. Eight flavonoids, a phenolic glycoside, and an alkaloid were enriched in the Willow Buds. The TFW exhibited significant antioxidant activity, with IC
Identifiants
pubmed: 36080462
pii: molecules27175695
doi: 10.3390/molecules27175695
pmc: PMC9457869
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Antioxidants
0
Flavonoids
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Basic research project of Education Department of Liaoning Province
ID : LJKQZ2021196
Organisme : Liaoning Provincial Natural Science Foundation program
ID : 2022-NLTS-17-01
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