Design, development, and testing of a voice-text mobile health application to support Tuberculosis medication adherence in Uganda.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2022
Historique:
received: 05 11 2021
accepted: 23 08 2022
entrez: 9 9 2022
pubmed: 10 9 2022
medline: 14 9 2022
Statut: epublish

Résumé

Tuberculosis (TB) continues to persist with a high disease burden globally. Non-adherence to treatment remains a major problem to TB control. In Uganda, one in every four TB patients does not adhere to their TB medication. The purpose of this study was to design, develop and assess implementation of a voice-text-based mobile application to support TB patients' adherence to medication. Design science research methodology (DSRM) was utilized to develop a voice-text-based mobile health application. Agile software methodology was used to achieve steps of DSRM that are; design and development. Focus group discussions (FGDs) and Key informant interviews (KIIs) were conducted and data analysed using thematic content analysis. During problem identification, Stigma, transport costs, being asymptomatic, drug side effects, lack of family support were identified as challenges affecting adherence. Technologies identified and used for the development of the voice-text application included; extensible mark-up language (XML) File, Apache server, Ubuntu Server, Hypertext Pre-processor, and jQuery. In the pilot study, 27 voice messages were broadcasted, 85.2% were delivered, 103 text messages were sent and 92.2% were delivered to the intended recipients. Voice-text message mobile health application can be used to reach a wider patient population and it has the capability of addressing some of the challenges affecting TB medication adherence.

Sections du résumé

BACKGROUND
Tuberculosis (TB) continues to persist with a high disease burden globally. Non-adherence to treatment remains a major problem to TB control. In Uganda, one in every four TB patients does not adhere to their TB medication. The purpose of this study was to design, develop and assess implementation of a voice-text-based mobile application to support TB patients' adherence to medication.
METHODS
Design science research methodology (DSRM) was utilized to develop a voice-text-based mobile health application. Agile software methodology was used to achieve steps of DSRM that are; design and development. Focus group discussions (FGDs) and Key informant interviews (KIIs) were conducted and data analysed using thematic content analysis.
RESULTS
During problem identification, Stigma, transport costs, being asymptomatic, drug side effects, lack of family support were identified as challenges affecting adherence. Technologies identified and used for the development of the voice-text application included; extensible mark-up language (XML) File, Apache server, Ubuntu Server, Hypertext Pre-processor, and jQuery. In the pilot study, 27 voice messages were broadcasted, 85.2% were delivered, 103 text messages were sent and 92.2% were delivered to the intended recipients.
CONCLUSIONS
Voice-text message mobile health application can be used to reach a wider patient population and it has the capability of addressing some of the challenges affecting TB medication adherence.

Identifiants

pubmed: 36084106
doi: 10.1371/journal.pone.0274112
pii: PONE-D-21-33327
pmc: PMC9462710
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0274112

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

AIDS Behav. 2011 Nov;15(8):1776-84
pubmed: 21739286
PLoS One. 2019 Jul 22;14(7):e0219891
pubmed: 31329610
BMC Res Notes. 2018 Oct 1;11(1):691
pubmed: 30285907
BMC Public Health. 2013 May 01;13:424
pubmed: 23634650
BMJ Glob Health. 2018 Oct 11;3(5):e001018
pubmed: 30364330
Health Policy. 2009 Feb;89(2):160-7
pubmed: 18599148
Tuberc Res Treat. 2014;2014:685982
pubmed: 25276424
PLoS Med. 2015 Sep 15;12(9):e1001876
pubmed: 26372470
Thorax. 2012 Jul;67(7):632-8
pubmed: 22403070
BMC Infect Dis. 2015 Sep 30;15:405
pubmed: 26423277
Am J Trop Med Hyg. 2015 Jun;92(6):1271-9
pubmed: 25846297
Psychol Addict Behav. 2013 Mar;27(1):315-21
pubmed: 22963375
AIDS. 2013 Aug 24;27(13):2166-8
pubmed: 23751260
ERJ Open Res. 2020 Apr 06;6(1):
pubmed: 32280670
Pathog Glob Health. 2015 Jul;109(5):221-7
pubmed: 26239760
J Health Popul Nutr. 2018 Jan 5;37(1):1
pubmed: 29304840
Pan Afr Med J. 2017 May 01;27:1
pubmed: 28748003
AIDS Behav. 2010 Jun;14(3):716-20
pubmed: 20054634
Bull World Health Organ. 2007 May;85(5):407-9
pubmed: 17639230
Health Expect. 2011 Sep;14(3):285-95
pubmed: 20860777
BMC Res Notes. 2015 Sep 29;8:503
pubmed: 26420164
PLoS One. 2012;7(5):e35908
pubmed: 22567119
Int J Environ Res Public Health. 2017 Sep 25;14(10):
pubmed: 28946683
PLoS One. 2018 Jun 27;13(6):e0198653
pubmed: 29949593

Auteurs

Kenneth Kidonge Katende (KK)

AIDS Clinical Trials Group, Data Department, Joint Clinical Research Centre, Kampala, Uganda.

Mercy R Amiyo (MR)

Department of Information Systems, School of Computing and Informatics Technology, College of Computing and Information Sciences, Makerere University, Kampala, Uganda.

Sarah Nabukeera (S)

Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.

Ian Mugisa (I)

AIDS Clinical Trials Group, Data Department, Joint Clinical Research Centre, Kampala, Uganda.

Patrick Kaggwa (P)

Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.

Stellah Namatovu (S)

Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.

Simon Peter Atwiine (SP)

Information Technology, Uganda Virus Research Institute, Entebbe, Uganda.

Simon Kasasa (S)

Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH