Real-world costs and dynamics of surveillance in patients who underwent surgery for low-risk branch duct intraductal papillary mucinous neoplasms.

Humans Carcinoma, Pancreatic Ductal / pathology Adenocarcinoma, Mucinous / pathology Retrospective Studies Pancreatic Neoplasms / pathology Risk Pancreatectomy
Branch-duct IPNM Cost-effectiveness EUS Intraductal papillary mucinous neoplasm Pancreas Pancreatic cystic neoplasm Pancreatic surgery

Journal

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
ISSN: 1532-2157
Titre abrégé: Eur J Surg Oncol
Pays: England
ID NLM: 8504356

Informations de publication

Date de publication:
01 2023
Historique:
received: 13 05 2022
revised: 22 06 2022
accepted: 26 08 2022
pubmed: 10 9 2022
medline: 24 1 2023
entrez: 9 9 2022
Statut: ppublish

Résumé

Surveillance costs and appropriateness of surgery of "low-risk" BD-IPMNs are relevant issues. In this study we evaluated the rate of correct indication for pancreatectomy defined as high grade dysplasia (HGD) at histology in 961 patients who underwent surveillance for a median of 5.1 years. Undertreatment and overtreatment were defined as invasive cancer and low grade dysplasia (LGD) at histology, respectively. Of the 66 patients (6.9%) who were operated, only 16 (23.8%) had a HGD while 40 (59.7%) had a LGD and 10 (14.9%) an invasive cancer, without differences regarding timing of surgery. The mean surveillance cost was € 194.9 ± 107.6 per patient-year, with a median cost of € 277.1 ± 148.2 in the correct surgery group compared with € 222.7 ± 111.6 and € 197 ± 102.7 in the overtreatment and undertreatment groups. The surveillance mean cost from diagnosis to surgery was € 854.8. Rate of appropriate surgery in BD-IPMNs under surveillance is low.

Identifiants

DOI: 10.1016/j.ejso.2022.08.033 PMID: 36085119
pubmed: 36085119
pii: S0748-7983(22)00644-8
doi: 10.1016/j.ejso.2022.08.033
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

137-141

Informations de copyright

Copyright © 2022. Published by Elsevier Ltd.

Auteurs

Domenico Tamburrino (D)

Division of Pancreatic and Transplant Surgery, Vita Salute San Raffaele University, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Milan, Italy. Electronic address: tamburrino.domenico@hsr.it.

Paolo Cortesi (P)

Research Centre on Public Health (CESP), University of Milano-Bicocca, Monza, Italy.

Rita Facchetti (R)

Research Centre on Public Health (CESP), University of Milano-Bicocca, Monza, Italy.

Nicolò de Pretis (N)

Department of Gastroenterology, Verona, Italy.

Enrique Pérez-Cuadrado-Robles (E)

Department of Hepato-Gastroenterology, Cliniques universitaires Saint-Luc, Brussels, Belgium; Department of Gastroenterology, Hôpital européen Georges-Pompidou, Paris, France.

Laura Uribarri-Gonzalez (L)

Department of Gastroenterology, Complejo Hospitalario de Navarra, Pamplona, Spain; Department of Gastroenterology, Hospital Universitario de Santiago de Compostela, Santiago de Compostela, Spain.

Zeeshan Ateeb (Z)

Pancreatic Surgery Unit, Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Universitetsjukhuset i Huddinge, Huddinge, Sweden.

Giulio Belfiori (G)

Division of Pancreatic and Transplant Surgery, Vita Salute San Raffaele University, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Milan, Italy.

Paolo Giorgio Arcidiacono (PG)

Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita-Salute San Raffaele University, Milan, Italy.

Lorenzo Giovanni Mantovani (LG)

Research Centre on Public Health (CESP), University of Milano-Bicocca, Monza, Italy.

Marco Del Chiaro (M)

Division of Surgical Oncology, Department of Surgery, University of Colorado, Anschutz Medical Campus, Denver, CO, United States.

Johanna Laukkarinen (J)

Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Massimo Falconi (M)

Division of Pancreatic and Transplant Surgery, Vita Salute San Raffaele University, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Milan, Italy.

Stefano Crippa (S)

Division of Pancreatic and Transplant Surgery, Vita Salute San Raffaele University, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Milan, Italy. Electronic address: crippa.stefano@hsr.it.

Gabriele Capurso (G)

Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita-Salute San Raffaele University, Milan, Italy.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Real-world costs and dynamics of surveillance...
questionsmedicales.fr › Maladies endocriniennes › Tumeurs des glandes endocrines › Tumeurs du pancréas › Carcinome du canal pancréatique › Real-world costs and dynamics of surveillance...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Tumeurs kystiques, mucineuses et séreuses › Adénocarcinome mucineux › Real-world costs and dynamics of surveillance...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Real-world costs and dynamics of surveillance...
questionsmedicales.fr › Maladies endocriniennes › Tumeurs des glandes endocrines › Tumeurs du pancréas › Real-world costs and dynamics of surveillance...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Real-world costs and dynamics of surveillance...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie digestive › Pancréatectomie › Real-world costs and dynamics of surveillance...