Transcriptome profiles of latently- and reactivated HIV-1 infected primary CD4

HIV-1 latency reversal agents latently HIV-1 infected primary CD4+ T cells pooled data-analysis pooled data-analysis differentially expressed genes (pdaDEGs) primary CD4+ T cell models of HIV-1 latency reactivated HIV-1 infected primary CD4+ T cells transcriptome profile

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 08 04 2022
accepted: 13 07 2022
entrez: 12 9 2022
pubmed: 13 9 2022
medline: 14 9 2022
Statut: epublish

Résumé

The main obstacle to cure HIV-1 is the latent reservoir. Antiretroviral therapy effectively controls viral replication, however, it does not eradicate the latent reservoir. Latent CD4

Identifiants

pubmed: 36090997
doi: 10.3389/fimmu.2022.915805
pmc: PMC9459035
doi:

Types de publication

Systematic Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

915805

Informations de copyright

Copyright © 2022 Inderbitzin, Loosli, Opitz, Rusert and Metzner.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Anne Inderbitzin (A)

Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Life Science Zurich Graduate School, University of Zurich, Zurich, Switzerland.

Tom Loosli (T)

Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Life Science Zurich Graduate School, University of Zurich, Zurich, Switzerland.

Lennart Opitz (L)

Functional Genomics Center Zurich, Eidgenössische Technische Hochschule (ETH) Zürich/University of Zurich, Zurich, Switzerland.

Peter Rusert (P)

Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

Karin J Metzner (KJ)

Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

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