The molecular mechanisms of ferroptosis and its role in glioma progression and treatment.

combination therapy ferroptosis glioma progression molecular mechanism role

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2022
Historique:
received: 11 04 2022
accepted: 05 07 2022
entrez: 12 9 2022
pubmed: 13 9 2022
medline: 13 9 2022
Statut: epublish

Résumé

Ferroptosis is one of the programmed modes of cell death that has attracted widespread attention recently and is capable of influencing the developmental course and prognosis of many tumors. Glioma is one of the most common primary tumors of the central nervous system, but effective treatment options are very limited. Ferroptosis plays a critical role in the glioma progression, affecting tumor cell proliferation, angiogenesis, tumor necrosis, and shaping the immune-resistant tumor microenvironment. Inducing ferroptosis has emerged as an attractive strategy for glioma. In this paper, we review ferroptosis-related researches on glioma progression and treatment.

Identifiants

pubmed: 36091118
doi: 10.3389/fonc.2022.917537
pmc: PMC9450584
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

917537

Informations de copyright

Copyright © 2022 Lu, Zhou, Sun, Shafi, Ahmad, Sun and Dong.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Mengyang Lu (M)

Noncoding RNA and Cancer Lab, Faculty of Life Sciences, Shanghai University, Shanghai, China.
Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.

Yuanshuai Zhou (Y)

Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.

Linjuan Sun (L)

Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.
School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Shaheryar Shafi (S)

Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.
School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Nafees Ahmad (N)

Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan.

Minxuan Sun (M)

Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.

Jun Dong (J)

Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Classifications MeSH