The Effect of Cell Salvage on Bleeding and Transfusion Needs in Cardiac Surgery.
Journal
Anesthesiology research and practice
ISSN: 1687-6962
Titre abrégé: Anesthesiol Res Pract
Pays: United States
ID NLM: 101532982
Informations de publication
Date de publication:
2022
2022
Historique:
received:
19
06
2022
revised:
10
08
2022
accepted:
20
08
2022
entrez:
12
9
2022
pubmed:
13
9
2022
medline:
13
9
2022
Statut:
epublish
Résumé
Cell salvaging is well established in the blood management of cardiac patients, but there remain some concerns about its effects on perioperative bleeding and transfusion variables. This randomized controlled study investigated the potential effects of the centrifuged end-product on bleeding, transfusion rates, and other transfusion-related variables in adult cardiac surgery patients submitted to extracorporeal circulation. Patients were randomly chosen to receive (cell-salvage group, 99 patients) or not to receive (control group, 110 patients) the centrifuged product of a cell salvage apparatus. Bleeding and transfusion rates according to the universal definition of perioperative bleeding (UDPB) classification, postoperative hemoglobin, coagulation, and oxygenation indices were recorded and compared between the groups. Both groups had almost identical bleeding and transfusion rates (median value: 2 units of red blood cells (RBC) and no units of fresh frozen plasma (FFP) and platelets (PLT) for both groups, Within the study's constraints, the perioperative use of the cell salvage concentrate does not seem to affect bleeding or transfusion variables, although it could probably ameliorate postoperative oxygenation in adult cardiac surgery patients. A tendency to promote coagulation disturbances was detected.
Identifiants
pubmed: 36092853
doi: 10.1155/2022/3993452
pmc: PMC9458370
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3993452Informations de copyright
Copyright © 2022 Frixos Tachias et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
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