Effectiveness of a complex regional advance care planning intervention to improve care consistency with care preferences: study protocol for a multi-center, cluster-randomized controlled trial focusing on nursing home residents (BEVOR trial).

ACP facilitation Advance care planning Cluster-randomized controlled trial Complex intervention Nursing homes Patient-centered care Study protocol

Journal

Trials
ISSN: 1745-6215
Titre abrégé: Trials
Pays: England
ID NLM: 101263253

Informations de publication

Date de publication:
12 Sep 2022
Historique:
received: 22 05 2022
accepted: 20 07 2022
entrez: 12 9 2022
pubmed: 13 9 2022
medline: 15 9 2022
Statut: epublish

Résumé

According to recent legislation, facilitated advance care planning (ACP) for nursing home (NH) residents is covered by German sickness funds. However, the effects of ACP on patient-relevant outcomes have not been studied in Germany yet. This study investigates whether implementing a complex regional ACP intervention improves care consistency with care preferences in NH residents. This is a parallel-group cluster-randomized controlled trial (cRCT) with 48 NHs (≈ 3840 resident beds) between 09/2019 and 02/2023. The intervention group will receive a complex, regional ACP intervention aiming at sustainable systems redesign at all levels (individual, institutional, regional). The intervention comprises comprehensive training of ACP facilitators, implementation of reliable ACP processes, organizational development in the NH and other relevant institutions of the regional healthcare system, and education of health professionals caring for the residents. Control group NHs will deliver care as usual. Primary outcome is the hospitalization rate during the 12-months observation period. Secondary outcomes include the rate of residents whose preferences were known and honored in potentially life-threatening events, hospital days, index treatments like resuscitation and artificial ventilation, advance directives, quality of life, psychological burden on bereaved families, and costs of care. The NHs will provide anonymous, aggregated data of all their residents on the primary outcome and several secondary outcomes (data collection 1). For residents who have given informed consent, we will evaluate care consistency with care preferences and further secondary outcomes, based on chart reviews and short interviews with residents, surrogates, and carers (data collection 2). Process evaluation will aim to explain barriers and facilitators, economic evaluation the cost implications. This study has the potential for high-quality evidence on the effects of a complex regional ACP intervention on NH residents, their families and surrogates, NH staff, and health care utilization in Germany. It is the first cRCT investigating a comprehensive regional ACP intervention that aims at improving patient-relevant clinical outcomes, addressing and educating multiple institutions and health care providers, besides qualification of ACP facilitators. Thereby, it can generate evidence on the potential of ACP to effectively promote patient-centered care in the vulnerable population of frail and often chronically ill elderly. ClinicalTrials.gov ID NCT04333303 . Registered 30 March 2020.

Sections du résumé

BACKGROUND BACKGROUND
According to recent legislation, facilitated advance care planning (ACP) for nursing home (NH) residents is covered by German sickness funds. However, the effects of ACP on patient-relevant outcomes have not been studied in Germany yet. This study investigates whether implementing a complex regional ACP intervention improves care consistency with care preferences in NH residents.
METHODS METHODS
This is a parallel-group cluster-randomized controlled trial (cRCT) with 48 NHs (≈ 3840 resident beds) between 09/2019 and 02/2023. The intervention group will receive a complex, regional ACP intervention aiming at sustainable systems redesign at all levels (individual, institutional, regional). The intervention comprises comprehensive training of ACP facilitators, implementation of reliable ACP processes, organizational development in the NH and other relevant institutions of the regional healthcare system, and education of health professionals caring for the residents. Control group NHs will deliver care as usual. Primary outcome is the hospitalization rate during the 12-months observation period. Secondary outcomes include the rate of residents whose preferences were known and honored in potentially life-threatening events, hospital days, index treatments like resuscitation and artificial ventilation, advance directives, quality of life, psychological burden on bereaved families, and costs of care. The NHs will provide anonymous, aggregated data of all their residents on the primary outcome and several secondary outcomes (data collection 1). For residents who have given informed consent, we will evaluate care consistency with care preferences and further secondary outcomes, based on chart reviews and short interviews with residents, surrogates, and carers (data collection 2). Process evaluation will aim to explain barriers and facilitators, economic evaluation the cost implications.
DISCUSSION CONCLUSIONS
This study has the potential for high-quality evidence on the effects of a complex regional ACP intervention on NH residents, their families and surrogates, NH staff, and health care utilization in Germany. It is the first cRCT investigating a comprehensive regional ACP intervention that aims at improving patient-relevant clinical outcomes, addressing and educating multiple institutions and health care providers, besides qualification of ACP facilitators. Thereby, it can generate evidence on the potential of ACP to effectively promote patient-centered care in the vulnerable population of frail and often chronically ill elderly.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov ID NCT04333303 . Registered 30 March 2020.

Identifiants

pubmed: 36096948
doi: 10.1186/s13063-022-06576-3
pii: 10.1186/s13063-022-06576-3
pmc: PMC9465132
doi:

Banques de données

ClinicalTrials.gov
['NCT04333303']

Types de publication

Clinical Trial Protocol Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

770

Subventions

Organisme : Gemeinsame Bundesausschuss
ID : 01VSF18004

Investigateurs

Annika Albert (A)
Cornelia Alheid (C)
Claudia Bausewein (C)
Manuela Bruene (M)
Christian Calles (C)
Havva Camci (H)
Anne Daubmann (A)
Sophie Dahlke (S)
Stephanie Enger (S)
Berend Feddersen (B)
Gerd Felder (G)
Carsten Fluck (C)
Andreas Freienstein (A)
Theresa Freytag (T)
Angela Fuchs (A)
Andrea Icks (A)
Jürgen In der Schmitten (J)
Lena Hensel (L)
Eva Hummers (E)
Amra Hot (A)
Änne Kirchner (Ä)
Evelyn Kleinert (E)
Stephanie Klosterhalfen (S)
Henrike Kolbe (H)
Sonja Laag (S)
Henriette Langner (H)
Susanne Lezius (S)
Georg Marckmann (G)
Gabriele Meyer (G)
Jospeh Montalbo (J)
Friedemann Nauck (F)
Thuy Nguyen (T)
Andre Nowak (A)
Malte Ossenberg (M)
Christine Reisinger (C)
Sophia Reuter (S)
Nicola Rieder (N)
Tanja Riester (T)
Irina Rosu (I)
Holger Rösgen (H)
Katharina Salanta (K)
Zeinep Sassi (Z)
Jan Schildmann (J)
Thomas Schulenberg (T)
Michaela Schunk (M)
Daniela Sommer (D)
Henrikje Stanze (H)
Andreas Stöhr (A)
Anke Theuerkauf (A)
Nancy Thilo (N)
Jessica Tönjann (J)
Mahnaz Partowinia-Peters (M)
Sebastian Prommersberger (S)
Susanne Przybylla (S)
Christiane Vogel (C)
Markus Vomhof (M)
Janka Wilken (J)
Antonia Zapf (A)
Jennifer Zimprich (J)

Informations de copyright

© 2022. The Author(s).

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Auteurs

Kornelia Götze (K)

Institute of General Practice, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. goetzeko@uni-duesseldorf.de.

Claudia Bausewein (C)

Department of Palliative Medicine, Munich University Hospital, Munich, Germany.

Berend Feddersen (B)

Department of Palliative Medicine, Munich University Hospital, Munich, Germany.

Angela Fuchs (A)

Institute of General Practice, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Amra Hot (A)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Eva Hummers (E)

Department of General Practice, University Medical Center Göttingen, Göttingen, Germany.

Andrea Icks (A)

Institute for Health Services Research and Health Economics, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Änne Kirchner (Ä)

Institute of Health and Nursing Science, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

Evelyn Kleinert (E)

Department of General Practice, University Medical Center Göttingen, Göttingen, Germany.

Stephanie Klosterhalfen (S)

Institute of General Practice, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Henrike Kolbe (H)

Coordination Center for Clinical Trials - KKSD, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Sonja Laag (S)

Barmer Health Insurance, Wuppertal, Germany.

Henriette Langner (H)

Institute of Health and Nursing Science, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

Susanne Lezius (S)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Gabriele Meyer (G)

Institute of Health and Nursing Science, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

Joseph Montalbo (J)

Institute for Health Services Research and Health Economics, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Friedemann Nauck (F)

Department of Palliative Medicine, University Medical Center Göttingen, Göttingen, Germany.

Christine Reisinger (C)

Institute of Ethics, History and Theory of Medicine, Ludwig Maximilians University Munich, Munich, Germany.

Nicola Rieder (N)

Department of Palliative Medicine, University Medical Center Göttingen, Göttingen, Germany.

Jan Schildmann (J)

Institute for History and Ethics of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

Michaela Schunk (M)

Department of Palliative Medicine, Munich University Hospital, Munich, Germany.

Henrikje Stanze (H)

Department of Social and Nursing Science, City University of Applied Science Bremen, Bremen, Germany.

Christiane Vogel (C)

Institute for History and Ethics of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

Karl Wegscheider (K)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Antonia Zapf (A)

Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Georg Marckmann (G)

Institute of Ethics, History and Theory of Medicine, Ludwig Maximilians University Munich, Munich, Germany.

Jürgen In der Schmitten (J)

Institute of Family Medicine/General Practice, Medical Faculty, University of Duisburg-Essen, Essen, Germany.

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