Phenotype Analysis of Fused in Sarcoma Mutations in Amyotrophic Lateral Sclerosis.

Journal

Neurology. Genetics
ISSN: 2376-7839
Titre abrégé: Neurol Genet
Pays: United States
ID NLM: 101671068

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 01 03 2022
accepted: 26 05 2022
entrez: 15 9 2022
pubmed: 16 9 2022
medline: 16 9 2022
Statut: epublish

Résumé

Pathogenic variations in fused in sarcoma We identified and cross-sectionally analyzed 22 Survival of We observed specific genotype-phenotype correlations of

Sections du résumé

Background and Objectives UNASSIGNED
Pathogenic variations in fused in sarcoma
Methods UNASSIGNED
We identified and cross-sectionally analyzed 22
Results UNASSIGNED
Survival of
Discussion UNASSIGNED
We observed specific genotype-phenotype correlations of

Identifiants

DOI: 10.1212/NXG.0000000000200011 PMID: 36105853 PMC: PMC9469212
pubmed: 36105853
doi: 10.1212/NXG.0000000000200011
pii: NNG-2022-200014
pmc: PMC9469212
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e200011

Informations de copyright

Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.

Références

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Aug;18(5-6):451-453
pubmed: 28288521
Neurobiol Aging. 2009 Aug;30(8):1272-5
pubmed: 19450904
Neurol Sci. 2021 Mar;42(3):1207-1209
pubmed: 33001405
Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Dec;1(5):293-9
pubmed: 11464847
Science. 2009 Feb 27;323(5918):1205-8
pubmed: 19251627
J Neurol Neurosurg Psychiatry. 2020 Mar;91(3):323-324
pubmed: 31694878
Nat Med. 2022 Jan;28(1):104-116
pubmed: 35075293
Neurobiol Aging. 2011 Dec;32(12):2323.e27-40
pubmed: 20674093
J Neurol Neurosurg Psychiatry. 2017 Jul;88(7):540-549
pubmed: 28057713
Nat Med. 2019 May 30;:
pubmed: 32467611
Neurology. 2019 Sep 3;93(10):e984-e994
pubmed: 31409738
Mol Ther. 2021 Dec 1;29(12):3345-3358
pubmed: 33839324
Neuromuscul Disord. 2012 Jan;22(1):73-5
pubmed: 21907581
Science. 2009 Feb 27;323(5918):1208-1211
pubmed: 19251628
Mol Neurodegener. 2016 Jan 22;11:8
pubmed: 26795035
Amyotroph Lateral Scler Frontotemporal Degener. 2022 Feb;23(1-2):128-136
pubmed: 33879000
J Biol Chem. 2013 Aug 30;288(35):25266-25274
pubmed: 23867462
Ann Clin Transl Neurol. 2019 Dec;6(12):2384-2394
pubmed: 31682085
Dis Model Mech. 2015 Jul 1;8(7):755-66
pubmed: 26035390
Ann Neurol. 2022 Jan;91(1):13-20
pubmed: 34704267
Rev Neurol (Paris). 2021 Apr;177(4):333-340
pubmed: 33036763
Neurobiol Aging. 2021 Jul;103:130.e1-130.e7
pubmed: 33637330
Muscle Nerve. 2016 Sep;54(3):398-404
pubmed: 26823199
Hum Mutat. 2013 Jun;34(6):812-26
pubmed: 23559573
Neurology. 2021 Jan 26;96(4):e600-e609
pubmed: 33208543
Amyotroph Lateral Scler Frontotemporal Degener. 2016;17(3-4):249-52
pubmed: 26972116
Clin Genet. 2017 Sep;92(3):267-273
pubmed: 28429524
Brain Behav. 2020 Jun;10(6):e01625
pubmed: 32307925
Neurology. 2012 Nov 6;79(19):1983-9
pubmed: 23100398

Auteurs

Maurizio Grassano (M)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Giorgia Brodini (G)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Giovanni De Marco (G)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Federico Casale (F)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Giuseppe Fuda (G)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Paolina Salamone (P)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Maura Brunetti (M)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Luca Sbaiz (L)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Salvatore Gallone (S)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Paolo Cugnasco (P)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Alessandro Bombaci (A)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Rosario Vasta (R)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Umberto Manera (U)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Antonio Canosa (A)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Cristina Moglia (C)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Andrea Calvo (A)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Bryan J Traynor (BJ)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Adriano Chio (A)

ALS Center (M.G., G.B., G.D.M., F.C., G.F., P.S., P.C., A.B., R.V., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), ''Rita Levi Montalcini'' Department of Neuroscience, University of Turin, Italy; Neuromuscular Diseases Research Section (M.G., B.J.T.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD; Laboratory of Genetics (M.B., L.S.), Department of Clinical Pathology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino; S.C. Neurologia 1U (S.G., U.M., Antonio Canosa, C.M., Andrea Calvo, Adriano Chio), Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy; Reta Lila Weston Institute (B.J.T.), UCL Queen Square Institute of Neurology, University College London, United Kingdom; Department of Neurology (B.J.T.), Johns Hopkins University Medical Center, Baltimore; National Institute of Neurological Disorders and Stroke (B.J.T.), NIH, Bethesda; ASO Rapid Development Laboratory (B.J.T.), Therapeutics Development Branch, National Center for Advancing Translational Sciences, NIH, Rockville, MD; and Institute of Cognitive Sciences and Technologies (Adriano Chio), National Council of Research, Rome, Italy.

Classifications MeSH