Effects of supplementation with low-dose group B vitamins on clinical and biochemical parameters in critically ill patients with COVID-19: a randomized clinical trial.
COVID-19
critically ill patients
vitamin B
Journal
Expert review of anti-infective therapy
ISSN: 1744-8336
Titre abrégé: Expert Rev Anti Infect Ther
Pays: England
ID NLM: 101181284
Informations de publication
Date de publication:
28 Sep 2022
28 Sep 2022
Historique:
pubmed:
16
9
2022
medline:
16
9
2022
entrez:
15
9
2022
Statut:
aheadofprint
Résumé
: This study aimed to check the effect of supplementation with low-dose group B vitamins on clinical and biochemical parameters on patients with coronavirus disease 2019 (COVID-19). : This double-blind, randomized clinical trial was carried out on 85 critically ill patients with COVID-19. All patients received high protein prescriptions of 30 kcal/kg/d by enteral nutrition. The intervention group ( : Vitamin B supplementation had no effects on the biochemical and pathological parameters including kidney function, arterial blood gas parameters, Glasgow coma scale, cell blood count, and serum electrolytes of the intervention group compared with the control group. The 30-day mortality was insignificantly lower in the intervention group than in the control group (83.3% against 96.1%, P = 0.07). The mortality rate of patients with COVID-19 might be improved by low-dose vitamin B supplementation.
Sections du résumé
BACKGROUND
UNASSIGNED
: This study aimed to check the effect of supplementation with low-dose group B vitamins on clinical and biochemical parameters on patients with coronavirus disease 2019 (COVID-19).
RESEARCH DESIGN AND METHOD
UNASSIGNED
: This double-blind, randomized clinical trial was carried out on 85 critically ill patients with COVID-19. All patients received high protein prescriptions of 30 kcal/kg/d by enteral nutrition. The intervention group (
RESULTS
UNASSIGNED
: Vitamin B supplementation had no effects on the biochemical and pathological parameters including kidney function, arterial blood gas parameters, Glasgow coma scale, cell blood count, and serum electrolytes of the intervention group compared with the control group. The 30-day mortality was insignificantly lower in the intervention group than in the control group (83.3% against 96.1%, P = 0.07).
CONCLUSIONS
UNASSIGNED
The mortality rate of patients with COVID-19 might be improved by low-dose vitamin B supplementation.
Identifiants
pubmed: 36108676
doi: 10.1080/14787210.2022.2125867
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM