Effects of early human immunodeficiency virus infection on cerebral white matter blood flow autoregulation.
Journal
AIDS (London, England)
ISSN: 1473-5571
Titre abrégé: AIDS
Pays: England
ID NLM: 8710219
Informations de publication
Date de publication:
01 02 2023
01 02 2023
Historique:
pmc-release:
01
02
2024
pubmed:
17
9
2022
medline:
23
12
2022
entrez:
16
9
2022
Statut:
ppublish
Résumé
Blood flow autoregulation in cerebral white matter was measured before and after acute nicardipine-induced changes in mean arterial pressure of 10-21% in 21 treatment naïve HIV-positive adults and 32 controls. The autoregulatory index (-% cerebral blood flow change/% mean arterial pressure change) was not different at baseline ( P = 0.71) or after 1 year of treatment ( n = 11, P = 0.17). We found no autoregulatory defect to explain the increased stroke risk or the development of cerebral white damage in people with HIV.
Identifiants
pubmed: 36111546
doi: 10.1097/QAD.0000000000003378
pii: 00002030-202302010-00017
pmc: PMC9780146
mid: NIHMS1834609
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
359-361Subventions
Organisme : NINDS NIH HHS
ID : R01 NS062754
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS082561
Pays : United States
Organisme : NINDS NIH HHS
ID : RF1 NS116565
Pays : United States
Informations de copyright
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
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