Primary cutaneous melanoma in Black patients: An analysis of 2464 cases from the National Cancer Database 2004-2018.
African American
African descent
NCDB
National Cancer Database
black patients
melanoma
skin cancer
skin of color
survival
Journal
Pigment cell & melanoma research
ISSN: 1755-148X
Titre abrégé: Pigment Cell Melanoma Res
Pays: England
ID NLM: 101318927
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
06
06
2022
accepted:
12
08
2022
pubmed:
17
9
2022
medline:
31
12
2022
entrez:
16
9
2022
Statut:
ppublish
Résumé
Melanoma in Black patients carries a poor prognosis. Due to its rarity, melanoma in this population has not been well characterized. This study evaluates survival predictors in Black patients with melanoma. This was a retrospective cohort study of Black patients with cutaneous melanoma from the National Cancer Database 2004-2018. Of the 2464 cases, melanoma was more common among females than males (57.1% vs. 42.9%, p < .001). Median Breslow depth was 1.8 mm (interquartile range 0.4-4.4). Lower extremities were the most common location (52.8%), followed by upper extremities (13.1%) along with otherwise specified/overlapping/other (13.1%), then by trunk (11.8%), and lastly head and neck (9.2%). Stage at diagnosis was I (30.7%), II (27.5%), III (24.1%), and IV (17.7%). Ulceration was observed in 41.4% of lesions. Acral lentiginous melanoma (ALM) was the most common specific histologic subtype (20.3%), followed by superficial spreading melanoma (9.4%). After adjusting for confounders, higher stages and primary site on the head and neck were the strongest independent predictors of worse overall survival. Melanoma in Black patients is most likely to appear on the lower extremities. A large portion (41.8%) presented with stage III or IV disease. ALM was the most common specific histologic subtype.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
42-52Informations de copyright
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Références
Adamson, A. S., Zhou, L., Baggett, C. D., Thomas, N. E., & Meyer, A. M. (2017). Association of delays in surgery for melanoma with insurance type. JAMA Dermatology, 153(11), 1106-1113. https://doi.org/10.1001/jamadermatol.2017.3338
American College of Surgeons. (2022). The National Cancer Database. https://www.facs.org/quality-programs/cancer/ncdb. Accessed March 25, 2022.
American Joint Committee on Cancer. (2002). Skin. In F. L. Greene, D. L. Page, I. D. Fleming, et al. (Eds.), AJCC cancer staging manual (6th ed.). Springer. https://doi.org/10.1007/978-1-4757-3656-4
American Joint Committee on Cancer. (2010). AJCC cancer staging manual (7th ed.). Springer.
American Joint Committee on Cancer. (2017). Skin. In M. B. Amin, S. B. Edge, et al. (Eds.), AJCC cancer staging manual, 8th edition supplement (8th ed.). Springer International Publishing: American Joint Commission on Cancer.
Amini, A., Rusthoven, C. G., Waxweiler, T. V., Jones, B. L., Fisher, C. M., Karam, S. D., & Raben, D. (2016). Association of health insurance with outcomes in adults ages 18 to 64 years with melanoma in the United States. Journal of the American Academy of Dermatology, 74(2), 309-316. https://doi.org/10.1016/j.jaad.2015.09.054
Behbahani, S., Maddukuri, S., Cadwell, J. B., Lambert, W. C., & Schwartz, R. A. (2020). Gender differences in cutaneous melanoma: Demographics, prognostic factors, and survival outcomes. Dermatologic Therapy, 33(6), e14131. https://doi.org/10.1111/dth.14131
Behbahani, S., Malerba, S., & Samie, F. H. (2021). Racial and ethnic differences in the clinical presentation and outcomes of acral lentiginous melanoma. British Journal of Dermatology, 184(1), 158-160. https://doi.org/10.1111/bjd.19406
Benchimol, E. I., Smeeth, L., Guttmann, A., Harron, K., Moher, D., Petersen, I., Sørensen, H. T., von Elm, E., Langan, S. M., & RECORD Working Committee. (2015). The REporting of studies conducted using observational routinely-collected health data (RECORD) statement. PLoS Medicine, 12(10), e1001885. https://doi.org/10.1371/journal.pmed.1001885
Bradford, P. T., Goldstein, A. M., McMaster, M. L., & Tucker, M. A. (2009). Acral lentiginous melanoma: Incidence and survival patterns in the United States, 1986-2005. Archives of Dermatology, 145(4), 427-434. https://doi.org/10.1001/archdermatol.2008.609
Byrd, K. M., Wilson, D. C., Hoyler, S. S., & Peck, G. L. (2004). Advanced presentation of melanoma in African Americans. Journal of the American Academy of Dermatology, 50(1), 21-24. https://doi.org/10.1016/S0190-9622(03)02091-7
Carter, T. M., Strassle, P. D., Ollila, D. W., Stitzenberg, K. B., Meyers, M. O., & Maduekwe, U. N. (2021). Does acral lentiginous melanoma subtype account for differences in patterns of care in black patients? The American Journal of Surgery, 221(4), 706-711. https://doi.org/10.1016/j.amjsurg.2020.12.040
Cormier, J. N., Xing, Y., Ding, M., Lee, J. E., Mansfield, P. F., Gershenwald, J. E., Ross, M. I., & Du, X. L. (2006). Ethnic differences among patients with cutaneous melanoma. Archives of Internal Medicine, 166(17), 1907-1914. https://doi.org/10.1001/archinte.166.17.1907
Culp, M. B., & Lunsford, N. B. (2019). Melanoma among non-Hispanic black Americans. Preventing Chronic Disease, 16, E79. https://doi.org/10.5888/pcd16.180640
Dawes, S. M., Tsai, S., Gittleman, H., Barnholtz-Sloan, J. S., & Bordeaux, J. S. (2016). Racial disparities in melanoma survival. Journal of the American Academy of Dermatology, 75(5), 983-991. https://doi.org/10.1016/j.jaad.2016.06.006
Ezaldein, B. S. H. H., Grunseich, B. A. K., Jairam, B. S. V., & Ventura, M. D. A. (2015). Income-associated discrepancies in melanoma survival. Cancer Treatment Communications, 4, 143-147. https://doi.org/10.1016/j.ctrc.2015.08.008
Lyman, M., Mills, J. O., & Shipman, A. R. (2017). A dermatological questionnaire for general practitioners in England with a focus on melanoma; misdiagnosis in black patients compared to white patients. Journal of the European Academy of Dermatology and Venereology, 31(4), 625-628. https://doi.org/10.1111/jdv.13949
Mahendraraj, K., Sidhu, K., Lau, C. S. M., McRoy, G. J., Chamberlain, R. S., & Smith, F. O. (2017). Malignant melanoma in African-Americans: A population-based clinical outcomes study involving 1106 African-American patients from the surveillance, epidemiology, and end result (SEER) database (1988-2011). Medicine, 96(15), e6258. https://doi.org/10.1097/MD.0000000000006258
Mallin, K., Browner, A., Palis, B., Gay, G., McCabe, R., Nogueira, L., Yabroff, R., Shulman, L., Facktor, M., Winchester, D. P., & Nelson, H. (2019). Incident cases captured in the National Cancer Database Compared with those in U.S. population based central cancer registries in 2012-2014. Annals of Surgical Oncology, 26(6), 1604-1612. https://doi.org/10.1245/s10434-019-07213-1
Mohanty, S., & Bilimoria, K. Y. (2014). Comparing national cancer registries: The National Cancer Data Base (NCDB) and the surveillance, epidemiology, and end results (SEER) program: Editorial. Journal of Surgical Oncology, 109(7), 629-630. https://doi.org/10.1002/jso.23568
Myles, Z. M., Buchanan, N., King, J. B., Singh, S., White, A., Wu, M., & Ajani, U. (2012). Anatomic distribution of malignant melanoma on the non-Hispanic black patient, 1998-2007. Journal of Surgical Oncology, 148(7), 797-801. https://doi.org/10.1001/archdermatol.2011.3227
Paulson, K. G., Gupta, D., Kim, T. S., Veatch, J. R., Byrd, D. R., Bhatia, S., Wojcik, K., Chapuis, A. G., Thompson, J. A., Madeleine, M. M., & Gardner, J. M. (2020). Age-specific incidence of melanoma in the United States. JAMA Dermatology, 156(1), 57-64. https://doi.org/10.1001/jamadermatol.2019.3353
Qian, Y., Johannet, P., Sawyers, A., Yu, J., Osman, I., & Zhong, J. (2021). The ongoing racial disparities in melanoma: An analysis of the surveillance, epidemiology, and end results database (1975-2016). Journal of the American Academy of Dermatology, 84(6), 1585-1593. https://doi.org/10.1016/j.jaad.2020.08.097
Quan, H., Li, B., Couris, C. M., Fushimi, K., Graham, P., Hider, P., Januel, J. M., & Sundararajan, V. (2011). Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. American Journal of Epidemiology, 173(6), 676-682. https://doi.org/10.1093/aje/kwq433
Tod, B. M., Kellett, P. E., Singh, E., Visser, W. I., Lombard, C. J., & Wright, C. Y. (2019). The incidence of melanoma in South Africa: An exploratory analysis of National Cancer Registry data from 2005 to 2013 with a specific focus on melanoma in black Africans. South African Medical Journal, 109(4), 246-253. https://doi.org/10.7196/SAMJ.2019.v109i4.13565
Tripathi, R., Archibald, L. K., Mazmudar, R. S., Conic, R. R. Z., Rothermel, L. D., Scott, J. F., & Bordeaux, J. S. (2020). Racial differences in time to treatment for melanoma. Journal of the American Academy of Dermatology, 83(3), 854-859. https://doi.org/10.1016/j.jaad.2020.03.094
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., & Vandenbroucke, J. P. (2008). The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. Journal of Clinical Epidemiology, 61(4), 344-349. https://doi.org/10.1016/j.jclinepi.2007.11.008
Wang, Y., Zhao, Y., & Ma, S. (2016). Racial differences in six major subtypes of melanoma: Descriptive epidemiology. BMC Cancer, 16(1), 691. https://doi.org/10.1186/s12885-016-2747-6
Ward-Peterson, M., Acuña, J. M., Alkhalifah, M. K., Nasiri, A. M., al-Akeel, E. S., Alkhaldi, T. M., Dawari, S. A., & Aldaham, S. A. (2016). Association between race/ethnicity and survival of melanoma patients in the United States over 3 decades: A secondary analysis of SEER data. Medicine, 95(17), e3315. https://doi.org/10.1097/MD.0000000000003315
Wu, X. C., Eide, M. J., King, J., Saraiya, M., Huang, Y., Wiggins, C., Barnholtz-Sloan, J. S., Martin, N., Cokkinides, V., Miller, J., Patel, P., Ekwueme, D. U., & Kim, J. (2011). Racial and ethnic variations in incidence and survival of cutaneous melanoma in the United States, 1999-2006. Journal of the American Academy of Dermatology, 65(5), S26.e1-S26.e13. https://doi.org/10.1016/j.jaad.2011.05.034
Yuan, T. A., Lu, Y., Edwards, K., Jakowatz, J., Meyskens, F., & Liu-Smith, F. (2019). Race-, age-, and anatomic site-specific gender differences in cutaneous melanoma suggest differential mechanisms of early- and late-onset melanoma. International Journal of Environmental Research and Public Health, 16(6), 908. https://doi.org/10.3390/ijerph16060908
Zell, J. A., Cinar, P., Mobasher, M., Ziogas, A., Meyskens, F. L., & Anton-Culver, H. (2008). Survival for patients with invasive cutaneous melanoma among ethnic groups: The effects of socioeconomic status and treatment. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 26(1), 66-75. https://doi.org/10.1200/JCO.2007.12.3604