Neurovascular coupling in patients with type 2 diabetes mellitus.
brain network
cerebral blood blow
cognitive impairment
functional MRI
neurovascular coupling
type 2 diabetes mellitus
Journal
Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824
Informations de publication
Date de publication:
2022
2022
Historique:
received:
23
06
2022
accepted:
15
08
2022
entrez:
19
9
2022
pubmed:
20
9
2022
medline:
20
9
2022
Statut:
epublish
Résumé
Functional and metabolic neural changes in Type 2 diabetes mellitus (T2DM) can be associated with poor cognitive performances. Here we analyzed the functional-metabolic neurovascular coupling (NVC) in the brain of T2DM patients. Thirty-three patients (70 ± 6 years, 15 males) with recent T2DM diagnosis and 18 healthy control (HC) subjects (65 ± 9 years, 9 males) were enrolled in a brain MRI study to identify the potential effects of T2DM on NVC. T2DM patients were either drug-naive (
Identifiants
pubmed: 36118711
doi: 10.3389/fnagi.2022.976340
pmc: PMC9476313
doi:
Types de publication
Journal Article
Langues
eng
Pagination
976340Informations de copyright
Copyright © 2022 Canna, Esposito, Tedeschi, Trojsi, Passaniti, di Meo, Polito, Maiorino, Paolisso, Cirillo and Rizzo.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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