Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study.
Journal
Journal of ophthalmology
ISSN: 2090-004X
Titre abrégé: J Ophthalmol
Pays: United States
ID NLM: 101524199
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
03
2022
accepted:
28
07
2022
entrez:
19
9
2022
pubmed:
20
9
2022
medline:
20
9
2022
Statut:
epublish
Résumé
18,335 eyes of 9,559 participants aged 40 to 80 years were included in the analysis. Median pupil diameter was 4.19 mm in right eyes and 4.12 mm in left eyes. A smaller pupil was associated with older age, hyperopic refractive error, previous cataract surgery, diabetes, obesity, and ACE inhibitor intake, whereas wider pupil was associated with female gender, arterial hypertension, intake of tricyclic antidepressants, and intake of SNRI and tetracyclic antidepressants. Socioeconomic status and smoking were not associated with pupil size. Individuals of older age, after cataract surgery, under therapy with ACE inhibitors and with diabetes have a smaller pupil. This should be taken into account when planning nonmydriatic fundus photography-based screening programs, for instance, for diabetic retinopathy.
Identifiants
pubmed: 36119137
doi: 10.1155/2022/9520512
pmc: PMC9481399
doi:
Types de publication
Journal Article
Langues
eng
Pagination
9520512Informations de copyright
Copyright © 2022 Marian Kiel et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest. There are no patents, products in development, or marketed products to declare. This does not alter the authors' adherence to all the journal policies on sharing data and materials. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Beutel ME received speaker honorarium from Pfizer Deutschland GmbH.
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