Outcomes of radical cystectomy in pT4 bladder cancer frail patients: Α high-volume single center study.
Outcomes of radical cystectomy in pT4 frail patients
Radical cystectomy in frail patients
Radical cystectomy in pT4 and frail patients
Radical cystectomy in pT4 patients
Journal
Journal of frailty, sarcopenia and falls
ISSN: 2459-4148
Titre abrégé: J Frailty Sarcopenia Falls
Pays: Greece
ID NLM: 101756655
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
accepted:
17
11
2021
entrez:
19
9
2022
pubmed:
20
9
2022
medline:
20
9
2022
Statut:
epublish
Résumé
This study aims to evaluate the effect of frailty in patients undergoing radical cystectomy (RC) for locally advanced bladder cancer. In this retrospective, single center study we evaluated 51 patients with pT4 bladder cancer treated with radical cystectomy between 2016-2020. Patient frailty was assessed with the Clinical Frailty Scale (CFS). Furthermore, six separate parameters (early mortality index within 30 days after surgery, death after one year, length of stay, respiratory complications, readmission index, total hospital charges) were also evaluated. The patients were categorized on three groups (Group 1, 2, 3) based on the CFS. A total of 51 pT4 RC patients were included in the study. Mean age was 75.6 years. Early mortality rate at 30 days after surgery was low all the groups. One year mortality rate was higher in Group 2 (22%) and 3 (69%). The length of stay and the number of patients with respiratory complications were also higher in the frailer groups. 30 days readmission rate was 22% in Group 2 and 38% in Group 3. Preoperative frailty is associated with worse postoperative results after RC. CFS is an objective tool for patient risk stratification and can predict postoperative complications and mortality.
Identifiants
pubmed: 36119554
doi: 10.22540/JFSF-07-147
pii: JFSF-7-147
pmc: PMC9433942
doi:
Types de publication
Journal Article
Langues
eng
Pagination
147-150Informations de copyright
Copyright: © 2022 Hylonome Publications.
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