Deep sedation vs. general anesthesia for transcatheter tricuspid valve repair.
TriClip
conscious sedation
deep sedation
general anesthesia
tricuspid valve regurgitation
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2022
2022
Historique:
received:
23
06
2022
accepted:
10
08
2022
entrez:
19
9
2022
pubmed:
20
9
2022
medline:
20
9
2022
Statut:
epublish
Résumé
Transcatheter tricuspid valve repair (TTVr) is routinely performed under general anesthesia (GA). This study aimed to investigate whether TTVr procedures can be performed effectively and safely without GA but using deep sedation (DS). We performed a retrospective analysis of 104 patients from three centers who underwent TTVr between 2020 and 2021. The primary performance endpoints were technical success and severity of TR assessed at the time of discharge. The safety outcome was a composite of in-hospital complications, including occurrence of death, conversion to surgery, major adverse cardiac and cerebrovascular events, major vascular complications, or occurrence of pneumonia. Sixty-four procedures were performed in GA and 40 procedures were performed in DS. The groups did not differ in age, EuroScore II, TR severity, ventricular function, or hemodynamic parameters. Technical success was achieved in 92.5% of the patients in the DS group and in 93.6% of the patients in the GA group ( Performing TTVr in DS was effective with similar procedural results, and was safe with similar low complication rates compared to GA.
Sections du résumé
Background
UNASSIGNED
Transcatheter tricuspid valve repair (TTVr) is routinely performed under general anesthesia (GA). This study aimed to investigate whether TTVr procedures can be performed effectively and safely without GA but using deep sedation (DS).
Methods
UNASSIGNED
We performed a retrospective analysis of 104 patients from three centers who underwent TTVr between 2020 and 2021. The primary performance endpoints were technical success and severity of TR assessed at the time of discharge. The safety outcome was a composite of in-hospital complications, including occurrence of death, conversion to surgery, major adverse cardiac and cerebrovascular events, major vascular complications, or occurrence of pneumonia.
Results
UNASSIGNED
Sixty-four procedures were performed in GA and 40 procedures were performed in DS. The groups did not differ in age, EuroScore II, TR severity, ventricular function, or hemodynamic parameters. Technical success was achieved in 92.5% of the patients in the DS group and in 93.6% of the patients in the GA group (
Conclusion
UNASSIGNED
Performing TTVr in DS was effective with similar procedural results, and was safe with similar low complication rates compared to GA.
Identifiants
pubmed: 36119730
doi: 10.3389/fcvm.2022.976822
pmc: PMC9471949
doi:
Types de publication
Journal Article
Langues
eng
Pagination
976822Informations de copyright
Copyright © 2022 Haurand, Kavsur, Ochs, Tanaka, Iliadis, Sugiura, Kelm, Nickenig, Baldus, Westenfeld, Becher, Pfister and Horn.
Déclaration de conflit d'intérêts
GN and SB have received research grants and speaker honoraria from Abbott, outside the submitted work. RP, CI, and PH have received travel support from Abbott, outside the submitted work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer TR declared a past collaboration with one of the authors RP to the handling editor.
Références
JACC Cardiovasc Imaging. 2019 Mar;12(3):532-553
pubmed: 30846126
Lancet. 2012 Sep 22;380(9847):1075-81
pubmed: 22998717
Eur Heart J Cardiovasc Imaging. 2020 May 1;21(5):511-521
pubmed: 32101610
EuroIntervention. 2021 Mar 19;16(16):1359-1365
pubmed: 33046436
Lancet. 2019 Nov 30;394(10213):2002-2011
pubmed: 31708188
Clin Pharmacokinet. 2018 Dec;57(12):1539-1558
pubmed: 30019172
J Cardiothorac Vasc Anesth. 2020 Jul;34(7):1942-1951
pubmed: 31761655
Eur Heart J. 2022 Feb 12;43(7):561-632
pubmed: 34453165
J Am Coll Cardiol. 2021 Jan 26;77(3):229-239
pubmed: 33478646
J Am Coll Cardiol. 2015 Jul 21;66(3):308-321
pubmed: 26184623
PLoS One. 2018 Jan 5;13(1):e0190590
pubmed: 29304185
JACC Case Rep. 2020 Jul 15;2(8):1109-1111
pubmed: 34317427
Catheter Cardiovasc Interv. 2017 Dec 1;90(7):1212-1219
pubmed: 28112459
J Am Coll Cardiol. 2021 Feb 2;77(4):345-356
pubmed: 33509390
Eur Heart J Cardiovasc Imaging. 2022 Jan 03;:
pubmed: 34977935