Genomic Profiling of a Case of Glioneuronal Tumor with Neuropil-like Islands.
genomic profiling
glioneuronal tumor with neuropil-like islands
Journal
Acta medica Okayama
ISSN: 0386-300X
Titre abrégé: Acta Med Okayama
Pays: Japan
ID NLM: 0417611
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
entrez:
19
9
2022
pubmed:
20
9
2022
medline:
23
9
2022
Statut:
ppublish
Résumé
Glioneuronal tumor with neuropil-like islands (GNTNI) is a very rare subtype of glioneuronal tumor. We present a case of a 62-year-old man with GNTNI. Two adjacent lesions in the left parietal lobe were removed by left parietal craniotomy. The histological findings were glial cell proliferation and scattered rosettes consisting of synaptophysin-positive and NeuN-positive cells, leading to the diagnosis of GNTNI. Target sequencing revealed a genetic alteration similar to glioblastoma, IDH-wild type, which suggested adjuvant therapies. There are few previous reports on the treatment of this disease, and the patient should be followed carefully.
Substances chimiques
Synaptophysin
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
473-477Déclaration de conflit d'intérêts
No potential conflict of interest relevant to this article was reported.
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