Ethosomes: A novel drug carrier.
Applications
Ethosomes
Proteins and peptides delivery
Transdermal delivery
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
received:
13
08
2022
accepted:
04
09
2022
entrez:
20
9
2022
pubmed:
21
9
2022
medline:
21
9
2022
Statut:
epublish
Résumé
Ethosomal systems are newer lipid vesicular carriers that have been around for 20 years, but over that period they have grown significantly as a means of transdermal drug delivery. They have a sizable amount of ethanol in them. These nanocarriers carry medicinal substances with various physicochemical qualities throughout the skin and deep skin layers. Since they were created in 1996, ethosomes have undergone substantial investigation; new substances have been added to their original composition, creating new varieties of ethosomal systems. These innovative carriers, which can be added to gels, patches, and lotions, are prepared using several novel methods. In addition to clinical trials, many in vivo models are employed to assess the effectiveness of dermal/transdermal administration. This review focuses on different generation of ethosomes and their comparison with other conventional liposomes.
Identifiants
pubmed: 36124209
doi: 10.1016/j.amsu.2022.104595
pii: S2049-0801(22)01355-3
pmc: PMC9482122
doi:
Types de publication
Journal Article
Langues
eng
Pagination
104595Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
Références
Int J Pharm. 2005 Jul 14;298(1):1-12
pubmed: 15896932
Expert Opin Drug Deliv. 2014 Mar;11(3):393-407
pubmed: 24392787
Curr Drug Deliv. 2014;11(3):332-7
pubmed: 24428443
Nat Rev Drug Discov. 2004 Feb;3(2):115-24
pubmed: 15040576
Drug Deliv Transl Res. 2011 Feb;1(1):53-65
pubmed: 25787889
Int J Nanomedicine. 2016 May 25;11:2279-304
pubmed: 27307730
J Antimicrob Chemother. 2005 Jun;55(6):989-94
pubmed: 15857943
Int J Pharm. 2005 Nov 23;305(1-2):90-104
pubmed: 16199131
Colloids Surf B Biointerfaces. 2012 Apr 1;92:299-304
pubmed: 22205066
Eur J Pharm Biopharm. 2003 May;55(3):271-7
pubmed: 12754000
Nat Biotechnol. 2008 Nov;26(11):1261-8
pubmed: 18997767
Life Sci. 1980 May 5;26(18):1473-7
pubmed: 6893068
AAPS PharmSciTech. 2008;9(3):860-5
pubmed: 18649143
Pharm Dev Technol. 2015 Jun;20(4):473-89
pubmed: 24490793
Materials (Basel). 2020 Nov 21;13(22):
pubmed: 33233413
Int J Pharm. 2003 Jan 16;250(2):313-25
pubmed: 12527159
Biochim Biophys Acta. 1992 Feb 17;1104(1):226-32
pubmed: 1550849
J Control Release. 2000 Apr 3;65(3):403-18
pubmed: 10699298
Drug Deliv. 2005 Sep-Oct;12(5):297-303
pubmed: 16188729