Acute Liver Injury in the setting of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome with Cocaine as suspected culprit agent: A case report.
Acute liver injury
Cocaine
Drug reaction with eosinophilia and systemic symptoms syndrome
Eosinophilia
Journal
Clinics and research in hepatology and gastroenterology
ISSN: 2210-741X
Titre abrégé: Clin Res Hepatol Gastroenterol
Pays: France
ID NLM: 101553659
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
13
07
2022
revised:
14
09
2022
accepted:
15
09
2022
pubmed:
21
9
2022
medline:
10
11
2022
entrez:
20
9
2022
Statut:
ppublish
Résumé
Drug Reaction with Eosinophilia and Systemic Response (DRESS) syndrome is a rare hypersensitivity reaction characterized by rash, fever, lymphadenopathy, and visceral involvement. The liver is frequently involved in DRESS, with increased liver enzymes and hepatomegaly. Over 40 drugs have been implicated in the induction of DRESS, however other illicit substances have also been linked to this. Prompt identification of this syndrome is imperative for management. We report the case of patient presenting with acute liver injury and eosinophilia, who developed a rash meeting criterion for DRESS, with Cocaine as the suspected culprit agent, and was successfully treated with conservative measures.
Identifiants
pubmed: 36126865
pii: S2210-7401(22)00157-7
doi: 10.1016/j.clinre.2022.102023
pii:
doi:
Substances chimiques
Cocaine
I5Y540LHVR
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
102023Informations de copyright
Copyright © 2022 Elsevier Masson SAS. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.