Mitigating the impact of air pollution on dementia and brain health: Setting the policy agenda.

Air pollution Brain health Complex systems theory Dementia Public policy Social and health inequalities

Journal

Environmental research
ISSN: 1096-0953
Titre abrégé: Environ Res
Pays: Netherlands
ID NLM: 0147621

Informations de publication

Date de publication:
12 2022
Historique:
received: 30 06 2022
revised: 13 09 2022
accepted: 14 09 2022
pubmed: 22 9 2022
medline: 14 10 2022
entrez: 21 9 2022
Statut: ppublish

Résumé

Emerging research suggests exposure to high levels of air pollution at critical points in the life-course is detrimental to brain health, including cognitive decline and dementia. Social determinants play a significant role, including socio-economic deprivation, environmental factors and heightened health and social inequalities. Policies have been proposed more generally, but their benefits for brain health have yet to be fully explored. Over the course of two years, we worked as a consortium of 20+ academics in a participatory and consensus method to develop the first policy agenda for mitigating air pollution's impact on brain health and dementia, including an umbrella review and engaging 11 stakeholder organisations. We identified three policy domains and 14 priority areas. Research and Funding included: (1) embracing a complexities of place approach that (2) highlights vulnerable populations; (3) details the impact of ambient PM Given the pressing issues of brain health, dementia and air pollution, setting a policy agenda is crucial. Policy needs to be matched by scientific evidence and appropriate guidelines, including bespoke strategies to optimise impact and mitigate unintended consequences. The agenda provided here is the first step toward such a plan.

Sections du résumé

BACKGROUND
Emerging research suggests exposure to high levels of air pollution at critical points in the life-course is detrimental to brain health, including cognitive decline and dementia. Social determinants play a significant role, including socio-economic deprivation, environmental factors and heightened health and social inequalities. Policies have been proposed more generally, but their benefits for brain health have yet to be fully explored.
OBJECTIVE AND METHODS
Over the course of two years, we worked as a consortium of 20+ academics in a participatory and consensus method to develop the first policy agenda for mitigating air pollution's impact on brain health and dementia, including an umbrella review and engaging 11 stakeholder organisations.
RESULTS
We identified three policy domains and 14 priority areas. Research and Funding included: (1) embracing a complexities of place approach that (2) highlights vulnerable populations; (3) details the impact of ambient PM
CONCLUSION
Given the pressing issues of brain health, dementia and air pollution, setting a policy agenda is crucial. Policy needs to be matched by scientific evidence and appropriate guidelines, including bespoke strategies to optimise impact and mitigate unintended consequences. The agenda provided here is the first step toward such a plan.

Identifiants

pubmed: 36130664
pii: S0013-9351(22)01689-9
doi: 10.1016/j.envres.2022.114362
pii:
doi:

Substances chimiques

Air Pollutants 0
Particulate Matter 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

114362

Subventions

Organisme : Medical Research Council
ID : MR/S019669/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/T045221/1
Pays : United Kingdom

Informations de copyright

Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Brian Castellani (B)

Durham Research Methods Centre, Durham University, Stockton Road, Durham, DH1 3LE, United Kingdom; Centre for the Evaluation of Complexity Across the Nexus, University of Surrey, Guildford, GU2 7XH, United Kingdom; Wolfson Research Institute for Health and Wellbeing, Durham University, Stockton Road, DH1 3LE, United Kingdom; Department of Sociology, Durham University, Stockton Road, Durham, DH1 3LE, United Kingdom. Electronic address: brian.c.castellani@durham.ac.uk.

Suzanne Bartington (S)

Institute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT, United Kingdom.

Jonathan Wistow (J)

Wolfson Research Institute for Health and Wellbeing, Durham University, Stockton Road, DH1 3LE, United Kingdom; Department of Sociology, Durham University, Stockton Road, Durham, DH1 3LE, United Kingdom.

Neil Heckels (N)

Research and Innovation Services, Durham University, Stockton Road, Durham, DH1 3LE, United Kingdom.

Amanda Ellison (A)

Wolfson Research Institute for Health and Wellbeing, Durham University, Stockton Road, DH1 3LE, United Kingdom; Department of Psychology, Durham University, Stockton Road, Durham, DH1 3LE, United Kingdom.

Martie Van Tongeren (M)

Centre for Occupational and Environmental Health, School of Health Sciences, University of Manchester, Manchester, M13 9PL, United Kingdom.

Steve R Arnold (SR)

School of Earth & Environment, University of Leeds, Leeds, LS2 9JT, United Kingdom.

Pete Barbrook-Johnson (P)

Centre for the Evaluation of Complexity Across the Nexus, University of Surrey, Guildford, GU2 7XH, United Kingdom; Environmental Change Institute, School of Geography and the Environment, University of Oxford, United Kingdom.

Martha Bicket (M)

Centre for the Evaluation of Complexity Across the Nexus, University of Surrey, Guildford, GU2 7XH, United Kingdom.

Francis D Pope (FD)

School of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.

Tom C Russ (TC)

Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, United Kingdom; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, United Kingdom.

Charlotte L Clarke (CL)

Department of Sociology, Durham University, Stockton Road, Durham, DH1 3LE, United Kingdom; School of Health in Social Science, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, United Kingdom.

Monica Pirani (M)

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, W2 1PG, London, United Kingdom.

Matthias Schwannauer (M)

School of Health in Social Science, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, United Kingdom.

Massimo Vieno (M)

UK Centre for Ecology & Hydrology, Bush Estate, Penicuik, Midlothian, EH26 0QB, United Kingdom.

Rachel Turnbull (R)

Academic Health Sciences Network, North East and North Cumbria, Nuns' Moor Road, Newcastle Upon Tyne NE4 5PL, United Kingdom.

Nigel Gilbert (N)

Centre for the Evaluation of Complexity Across the Nexus, University of Surrey, Guildford, GU2 7XH, United Kingdom.

Stefan Reis (S)

UK Centre for Ecology & Hydrology, Bush Estate, Penicuik, Midlothian, EH26 0QB, United Kingdom; University of Exeter Medical School, European Centre for Environment and Health, Knowledge Spa, Truro, TR1 3HD, United Kingdom; The University of Edinburgh, School of Chemistry, Level 3, Murchison House, 10 Max Born Crescent, The King's Buildings, West Mains Road, Edinburgh, EH9 3BF, United Kingdom.

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