Biomimetic hydroxyapatite paste for molar-incisor hypomineralization: A randomized clinical trial.
biomimetic hydroxyapatite
demineralization
enamel
molar-incisor hypomineralization
paste
randomized clinical trial
Journal
Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
revised:
26
08
2022
received:
05
04
2022
accepted:
16
09
2022
medline:
2
10
2023
pubmed:
23
9
2022
entrez:
22
9
2022
Statut:
ppublish
Résumé
The aim of this randomized clinical trial was to evaluate the desensitizing and remineralizing effect of a new zinc-hydroxyapatite-based paste in sites affected by molar-incisor hypomineralization (MIH), by assessing dental sensitivity, tooth wear, and periodontal indexes. Twenty-five patients with presence of 1 enamel demineralization of permanent molars and incisors in two different quadrants were recruited. After professional dental hygiene, a domiciliary hydroxyapatite-based paste was assigned and recommended to be applied on 2 MIH teeth in one random quadrant (test group), while the 2 contralateral MIH teeth did not undergo paste application (control group). The following primary outcomes were assessed: Plaque Control Record (PCR), Bleeding Index (BI), MIH Treatment Need Index (MIH-TNI), and Schiff Air Index (SAI). No significant inter- and intragroup differences were found for PI and BI, except for both intragroup T0-T1. For MIH-TNI, significant intergroup differences were detectable in the test group after 9 months of treatment. For SAI values, no significant differences were found in the control group, while in the test group, significant lower values were found after 1 and 3 months since baseline, respectively. Biomimetic zinc-hydroxyapatite showed a desensitizing effect when used to treat MIH.
Substances chimiques
Hydroxyapatites
0
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Pagination
2789-2798Informations de copyright
© 2022 The Authors. Oral Diseases published by Wiley Periodicals LLC.
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